SOURCE: AGI Therapeutics plc

November 19, 2007 07:11 ET

AGI Therapeutics plc announces PJC Conference

Dublin, Ireland--(Marketwire - November 19, 2007) -


AGI Therapeutics to present at 19th Annual Piper Jaffray Health Care Conference
                                  in New York

                   -- 1.30 p.m., Tuesday 27 November, 2007 --

Dublin, Ireland, November 19th 2007 - AGI Therapeutics plc ("AGI" or the "Company") (AIM, IEX: AGI), the speciality pharmaceutical company focused on gastrointestinal drug products, today announces that the Company's Chief Executive Officer, Dr. John Devane, will make a presentation at the 19th Annual Piper Jaffray Health Care Conference in New York.

Dr. Devane will deliver his presentation on Tuesday 27 November 2007 at 1.30 p.m. EDT (5.30 p.m. UKT). Investors may access an audio webcast of the presentation at http://www.piperjaffray.com/conferences.

A copy of the presentation will be available after the event on the AGI website at www.agitherapeutics.com under the "Investors: Publications" tab.


For further information please contact:

AGI Therapeutics plc                                Tel: +353 1 449 3254
David Kelly, Chief Financial Officer

Financial Dynamics - UK                             Tel: +44 (0) 20 7831 3113
Deborah Scott/Lara Mott

Piper Jaffray Limited                               Tel: +44 (0) 20 3142 8700
Neil Mackison
Will Carnwath

About AGI Therapeutics plc

AGI (the company) is a specialty pharmaceutical company which is focused on the development and commercialisation of differentiated drug products for gastrointestinal (GI) diseases and disorders. AGI's common shares are listed on the Alternative Investment Market of the London Stock Exchange (AIM) and on the Irish Enterprise Exchange of the Irish Stock Market (IEX) as AGI.

The company has a portfolio of product candidates derived from its Known Molecular Entity (KME) approach to drug re-profiling and development. RezularTM, AGI's lead product, is in Phase III clinical trials for the treatment of IBS-D.

About RezularTM (AGI-003)

Rezular (AGI-003) is an orally administered triple-action intestinal regulator, a first-in-class mechanism for the treatment of IBS-D. Rezular contains arverapamil, a single enantiomer moiety of the racemic drug verapamil. Unlike the currently available commercial forms of racemic verapamil (a mixture of two enantiomers), Rezular shows a dominant activity in treating the symptoms of IBS-D without the traditional cardiovascular actions of the racemic drug. The efficacy and safety of Rezular in IBS patients has already been established in a Phase II trial, the preliminary results of which were reported by the Company in 2006.

About IBS-D

Irritable bowel syndrome (IBS) is a functional disorder that comprises a cluster of gastrointestinal symptoms which are likely to be life long and which affect between 10% and 20% of the population in developed markets. IBS remains the most common diagnosis made by gastroenterologists and can lead to a substantial reduction in patients' quality of life, accompanied by considerable socio-economic and psychological consequences. Altered intestinal motility is a major component of IBS and patients are diagnosed and sub-typed according to their predominant symptom of bowel disturbance. Diarrhoea-predominant irritable bowel syndrome (IBS-D) is estimated to occur in one-third of all IBS patients. IBS-D represents a significant unmet medical need as there are currently few safe and effective therapeutic options available to these patients.

For further information please see www.agitherapeutics.com


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