ART Advanced Research Technologies Inc.
TSX : ARA

ART Advanced Research Technologies Inc.

May 17, 2006 12:54 ET

ART/eXplore Optix 'TM' Based Research Presented at European Society for Molecular Imaging Inaugural Meeting, Paris, France

MONTREAL, CANADA--(CCNMatthews - May 17, 2006) -

Abstract presented by Leiden University researchers demonstrates labelling of stem cells in the brain to detect beta-galactosidase activity, using the eXplore Optix system

ART Advanced Research Technologies Inc. ("ART") (TSX:ARA), a Canadian medical device company and a leader in optical molecular imaging products for the healthcare and pharmaceutical industries, is pleased to announce its participation at the first international meeting of the European Society for Molecular Imaging (ESMI), being held at the Museum d'Histoire Naturelle in Paris, France, from May 17 to 19, 2006.

At the ESMI conference, results obtained from ART's eXplore Optix system will be featured in a poster entitled "Far red imaging of beta-galactosidase (beta-gal) activity for stem cell detection in the brain" to be presented by a research team headed by Dr. Clemens W.G.M. Lowik, head of the Endocrinology Research Laboratory at the Leiden University Medical Center (LUMC) in the Netherlands. Researchers wanted to adapt a widely used genetic reporter system based on beta-gal activity to optical approaches. To do this, they implanted beta-gal and luciferase expressing stem cells into the left hemisphere of the mouse brain. Results obtained using the eXplore Optix system confirmed the presence of beta-gal -expressing stem cells in the same hemisphere 10 days after the implantation, thereby indicating that beta-gal may be successfully employed for in vivo imaging of deep-lying beta-gal-expressing cells.

"These findings by the research team at Leiden University go further in establishing the value of eXplore Optix in the lab," said Micheline Bouchard, ART's President and CEO. "By developing and validating reporter constructs involving beta-galactosidase, scientists will be able to then express these constructs in cell lines using non-invasive imaging technologies such as the ones developed by ART, and follow the trafficking and fate of the beta-gal-expressing genes," added Ms. Bouchard.

About ART

ART Advanced Research Technologies Inc. is a leader in optical molecular imaging products for the healthcare and pharmaceutical industries. ART has developed products in medical imaging, medical diagnostics, disease research, and drug discovery with the goal of bringing new and better treatments to patients faster. eXplore Optix™, an optical molecular imaging device designed for monitoring physiological changes in living systems at the preclinical study phases of new drugs, is distributed by GE Healthcare and is used by industry and academic leaders worldwide. SoftScan®, an optical medical imaging device, is designed to improve the diagnosis and treatment of breast cancer. ART is commercializing these products in a global strategic alliance with GE Healthcare, a world leader in mammography and imaging. Finally, the Fenestra™ line of molecular imaging contrast products provide image enhancement for a wide range of preclinical Micro CT applications allowing scientists to see greater detail in their imaging studies, with potential extension into other major imaging modalities. ART's shares are listed on the TSX under the ticker symbol ARA. For more information on ART, visit our website at www.art.ca .

This press release may contain forward-looking statements subject to risks and uncertainties that would cause actual events to differ materially from expectations. These risks and uncertainties are described in ART Advanced Research Technologies Inc.'s regulatory filings with Canadian Securities Commissions and with the Securities and Exchange Commission in the United States.

www.art.ca

Contact Information

  • ART ADVANCED RESEARCH TECHNOLOGIES INC.
    Sebastien Gignac
    VP, Corporate Secretary and General Counsel
    sgignac@art.ca
    or
    ART ADVANCED RESEARCH TECHNOLOGIES INC.
    Jacques Bedard
    Chief Financial Officer
    (514) 832-0777
    jbedard@art.ca