NEW YORK, NEW YORK and HALIFAX, NOVA SCOTIA--(Marketwire - Oct. 5, 2010) - Immunovaccine Inc. (TSX VENTURE:IMV), a vaccine developer, and IRX Therapeutics, a developer of immune therapies to make cancer treatments better, announced today that the two companies have entered into a preclinical research collaboration to evaluate the combination of IRX's primary cell-derived biologic, IRX-2, and DepoVax™ - based therapeutic cancer vaccines. The goal of the research is to demonstrate that the combination of the two technologies generates a superior anti-tumor immune response and will provide the foundation for the development of the next generation of therapeutic cancer vaccines.
"This is a very exciting pre-clinical collaboration between two companies with promising immunotherapy technologies for cancer," says Dr. Neil Berinstein, Chief Scientific Officer of IRX Therapeutics. "Pre-clinical studies have already shown that IRX-2 can significantly enhance immune response triggered by peptide and other cancer vaccine platforms and there is reason to believe that this will be further enhanced by combining IRX-2 with Immunovaccine's DepoVax- immune adjuvant platform."
"IRX-2 has interesting immune-modulating characteristics and we hope that combining it with DepoVax-based anti-cancer vaccines, the result will be a synergistic anti-tumor effect," said Marc Mansour, Ph.D., Vice President of Research and Development at Immunovaccine.
IRX's lead product candidate, IRX-2, is designed to broadly restore the immune system. This primary cell-derived biologic seeks to overcome cancer–induced immune suppression and restore anti-tumor response, vital steps in successfully treating cancer. The IRX-2 immunomodulator includes multiple cytokine proteins that work together synergistically to activate different arms of the immune system.
Immunovaccine's DepoVax™ platform is a lipid depot-based vaccine delivery and enhancement technology. This patented combination is a breakthrough in vaccine development because it raises unusually strong and long-lasting cellular or humoral immune responses.
About IRX Therapeutics
IRX Therapeutics is developing immune therapies that activate a patient's immune system to defeat cancer and related diseases. The lead platform technology, IRX-2, is designed to broadly restore the immune system by overcoming cancer-induced immune suppression. The targeted result is a durable anti-tumor response. IRX-2's safety profile allows it to be combined with cancer treatments, vaccines and therapies. The Company believes that its products can play an important role in helping a wide range of treatments improve and extend a patient's life. IRX Therapeutics' mission is to make cancer treatments better. For more information on IRX Therapeutics, please visit the Company's website at www.irxtherapeutics.com.
Immunovaccine Inc. (TSX VENTURE:IMV) is a clinical stage vaccine development company focused on the commercialization of its patented DepoVax™ vaccine delivery technology and product candidates. The company continues to strengthen its vaccine pipeline through licensing and strategic partnerships to develop therapeutic cancer and infectious disease vaccines. www.imvaccine.com
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