SOURCE: Medistem Laboratories

April 23, 2008 09:11 ET

Independent Confirmation That Menstrual Derived Stem Cells Have Utility in Fighting Disease

Medistem Applauds Japanese Publication

SAN DIEGO, CA and SCOTTSDALE, AZ--(Marketwire - April 23, 2008) - Medistem Laboratories, Inc. (OTCBB: MDSM), a biotechnology company dedicated to commercialization of its novel, universal donor, stem cell population, the Endometrial Regenerative Cell (ERC), applauds a recent publication from an independent Japanese group describing a similar cell type to Medistem's ERC from the same source: menstrual blood.

The recent publication "Hida et al. Novel Cardiac Precursor-Like Cells from Human Menstrual Blood-Derived Mesenchymal Cells. Stem Cells. 2008 Apr 17 [Epub ahead of print]" describes a stem cell population capable of not only becoming heart tissue in vitro, but also having ability to repair injured hearts in animal models of heart attacks.

"These recent data provide independent unbiased verification of the presence of functional stem cells in the menstrual blood," said Thomas Ichim, CEO of Medistem. He continued, "Our previous publication and patent applications describe a cell population with phenotypic and functional similarities to the cells of Hida et al. We are pleased to have aspects of our work successfully reproduced and advanced by scientists at the prestigious Keio University School of Medicine, Tokyo."

In November 2007, an international group of scientists lead by Medistem announced the discovery of the "Endometrial Regenerative Cell," a menstrual blood derived stem cell that could differentiate into 9 major tissues, produce high levels of therapeutic factors, and was capable of massive in-vitro expansion. The study, which is freely available at http://www.translational-medicine.com/content/5/1/57 was awarded BioMed Central's Best Publication in Medicine of 2007.

"Medistem has more than 15 patent families dealing with adult stem cell therapeutics. The recent publication provides additional support for the menstrual blood derived stem cell populations as a viable alternative to embryonic stem cells," said Neil Riordan, Chairman of Medistem.

About Medistem Laboratories

Medistem Laboratories is a biotechnology company founded to develop and commercialize technologies related to adult stem cell extraction, manipulation, and use for treating inflammatory and degenerative diseases. The company's lead product, the endometrial regenerative cell (ERC), is a "universal donor" stem cell derived from the menstrual blood that possesses the ability to differentiate into nine tissue types, produce large quantities of growth factors, and a large proliferative capacity. Due to Medistem's relationships and collaborative efforts with respected institutions, Medistem believes it is well positioned to be a leading developer of adult stem cell products.

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