SOURCE: Medistem Laboratories

November 15, 2007 09:30 ET

Medistem Announces Discovery of Novel Stem Cell Population in Menstrual Blood: Endometrial Regenerative Cells (ERC)

Cells Produce 100,000 Times the Number of Growth Factors Found in Cord Blood

SCOTTSDALE, AZ--(Marketwire - November 15, 2007) - Medistem Laboratories, Inc. (OTCBB: MDSM) (FRANKFURT: S2U) in collaboration with researchers from the University of Western Ontario, University of Alberta, and the Bio-Communications Research Institute, has published a paper describing a novel stem cell population derived from menstrual blood. The publication, entitled "Endometrial Regenerative Cells: A Novel Stem Cell Population" appeared in today's Journal of Translational Medicine and is freely available at http://www.translational-medicine.com/content/5/1/57

"I view the discovery of the Endometrial Regenerative Cell (ERC) as a great step forward in providing an ethical, easily accessible, and potentially highly useful adult stem cell for treatment of numerous degenerative conditions," said Dr. Xiaolong Meng, head of the research team. He continued, "ERC cells can be converted into basically all the major tissues of the body, including the liver, lung, pancreas, brain, heart, blood vessel, and muscle. Additionally, these cells produce 100,000 times the number of growth factors found in cord blood, opening the door to numerous regenerative applications."

This is the first publication in a peer-reviewed medical journal demonstrating that stem cells from the menstrual blood can generate numerous tissues and possess unique molecular and cellular characteristics.

"The ability to take a cell and differentiate it into the tissue type needed by the body creates a world of opportunity in the world of organ and tissue regeneration," said Neil Riordan, PhD, President and CEO of Medistem. He added, "With IP filed around the cell line, we have begun taking the next steps in the commercialization process. Currently, our collaborators at Western Ontario, Alberta, and the Bio-Communications Research Institute are doing a series of pre-clinical studies to establish efficacy data in a variety of indications. The indications currently being assessed include diabetes, liver cirrhosis, lung fibrosis, organ rejection, and multiple sclerosis. Should the data gathered prove strong in one or all the indications the next step will be to file INDs with the FDA and move into clinical trials," said Riordan.

About Medistem Laboratories, Inc.

Medistem Laboratories is a biotechnology company that discovers, develops, and commercializes adult stem cell products that address serious medical conditions. While drug discovery and development is its primary focus, Medistem has compiled a body of proprietary technologies it outlicenses to commercial entities in markets where stem cell administration is permissible. Due to its licensee relationships and collaborative efforts with respected institutions, Medistem believes it is well positioned to be a leading developer of adult stem cell products.

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