Novadaq Technologies Inc.

Novadaq Technologies Inc.

March 08, 2005 09:00 ET

Novadaq Reports Positive Results in CABG Study

TORONTO, ONTARIO--(Marketwire - March 8, 2005) - Novadaq™ Technologies today announced that Drs. Nimesh Desai and Stephen Fremes,
reported data on a 120-patient prospective study conducted at Sunnybrook and Women's College Health Sciences Centre in Toronto, Canada
using Novadaq’s proprietary Spy™ Intra-operative Imaging System for the assessment of graft quality during Coronary Artery Bypass
Surgery (CABG). The presentation, Achieving Perfect Coronary Bypass Patency With Intraoperative Angiography, was presented today at 54th
Annual Scientific Session of the American College of Cardiology, in Orlando, Florida.

"This data demonstrates that the SPY™ system identified major graft problems that would otherwise have gone unrecognized in 4% of the
patients operated on in this study. Another 4% of patients had minor graft revisions based on the SPY™ system images," said Dr. Desai.
"Given the increasing anatomic complexity of contemporary coronary bypass patients, this system provides a significant advance in
assuring the quality of coronary bypass surgery. Failure of bypass grafts during coronary bypass surgery is an underappreciated problem.
With this imaging technology, patients can be assured that their heart operation was truly successful."

Intra-operative graft angiography with the SPY™ system involves intravascular administration of fluorescent indocyanine green dye
(ICG) and visualization of the graft with dispersed laser light. In this study, 336 bypass grafts in 120 patients were examined using the
SPY™ system and a small subset of these grafts were also examined by x-ray angiography. The SPY™ system was demonstrated to be a
simple and highly reproducible procedure. The authors found that there was excellent agreement between independent evaluations of graft
patency (94% agreement) and need for graft revision (100% agreement). Pilot data also suggested that the SPY™ system provided similar
quality images to traditional x-ray angiography, a much more invasive procedure.

About the SPY™ Intra-operative Imaging System

Novadaq’s SPY™ Intra-operative Imaging System has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for use
during CABG surgery. SPY™ is the first intra-operative fluorescent imaging system that enables cardiac surgeons to confirm the
location of the coronary arteries and assess bypass graft functionality during coronary artery bypass procedures. The SPY™ system enables
the surgeon to view, record, replay, print and archive high quality real-time images of the coronary arteries and bypass grafts.

About Novadaq Technologies

Novadaq is focused on developing and marketing diagnostic and therapeutic medical devices for vascular imaging. Novadaq's SPY™ system
fulfils the unmet need of validating a successful revascularization during CABG surgery. Novadaq's ophthalmic product is aimed at the
diagnosis and treatment of wet Age-Related Macular Degeneration (AMD) by using the same core imaging technology that is used in the SPY™
Intra-operative Imaging System.

For more information, please visit the company's website at

Contact Information

  • Novadaq Technologies Inc.
    Arun Menawat
    President & CEO
    (905) 629-3822 x 202


    Media Relations:
    The Equicom Group
    Joanna Longo
    Vice President
    (416) 815-0700 x 233