Protherics PLC - Block Listing Return - 3


Cheshire, UK--(Marketwire - October 8, 2007) -

                               Protherics PLC
                         6 monthly Block Listing Return
                     Approved Executive Share Option Scheme
London, UK; Brentwood, TN; 8 October 2007 - Protherics PLC ("Protherics" or the "Company"), the international biopharmaceutical company focused on critical care and cancer, announces that, today, the following 6 monthly block listing return in respect of the Company's Approved Executive Share Option Scheme has been lodged with the FSA in accordance with Listing Rule 3.5.6.
Name of applicant:                  Protherics PLC

Name of scheme:                     Protherics PLC Approved Executive
                                    Share Option Scheme

Period of return:                   From:    9 April 2007
                                    To:      8 October 2007

Balance under scheme from previous 
return:                             335,299

The amount by which the block 
scheme has been increased, if the 
scheme has been increased since 
the date of the last return:        Nil

Number of securities 
issued/allotted under scheme 
during period:                      34,997

Balance under scheme not yet 
issued/allotted at end of period:   300,302

Number and class of securities 
originally listed and the           387,712 Ordinary Shares (date of
date of admission:                  admission: 8 April 2005)

Total number of securities in 
issue at the end of the period:     339,346,822

                                   |  Ends  |

For further information please contact:

Protherics
Nick Staples, Director of Corporate Affairs      +44 (0) 7919  480510
Julie Vickers, Company Secretary                 +44 (0) 1928  518010

Financial Dynamics - press enquiries
London: Ben Atwell, David Yates                  +44 (0) 20 7831 3113
New York: John Capodanno, Jonathan Birt          +1 212 850 5600

Or visit  www.protherics.com

                      This information is provided by RNS
            The company news service from the London Stock Exchange