Protherics PLC Notification of Major Interests in Shares London, UK; Brentwood, TN, US: 21 December 2007 - Protherics PLC ("Protherics" or the "Company"), the international biopharmaceutical company focused on critical care and cancer, announces that on 20 December 2007, in accordance with the Transparency Obligations Directive, a notification of interest in the ordinary share capital of the Company was received from AXA Investment Managers UK Limited on behalf of AXA S.A. and its Group Companies ("AXA"). The notification follows an increase in the Indirect holding of AXA. Details of the interest notified are as follows: 1. Reason for the notification (please tick the appropriate box or boxes) An acquisition of voting rights X An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Other (please specify): 2. Full name of person(s) subject to the AXA S.A., 25 Avenue Matignon, 75008 Paris and its notification obligation: group of companies. 3. Full name of shareholder(s) (if different from 2.): 4. Date of the transaction (and date on which 18 December 2007 the threshold is crossed or reached if different): 5. Date on which issuer notified: 19 December 2007 6. Threshold(s) that is/are crossed or reached: 14% 7. Notified details: A: Voting rights attached to shares Class/type of Situation previous to Resulting situation after the triggering transaction shares the Triggering transaction if possible using Number of Number of Number of Number of voting rights % of voting rights the ISIN CODE Shares Voting shares Rights Direct Direct Indirect Direct Indirect 0702920 43,726,012 43,726,012 741,666 741,666 48,854,003 0.22% 14.36% B: Financial Instruments Resulting situation after the triggering transaction Type of financial Expiration date Exercise/ Conversion Number of voting rights % of voting rights instrument Period/ Date that may be acquired if the instrument is exercised/ converted. Total (A+B) Number of voting rights % of voting rights 49,595,669 14.58% 8. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable : Name of Company/Fund Number of Shares % of issued share capital AXA UK Investment Co ICVC 551,929 0.16224 UK Smaller Companies Fund Indirect Sun Life Pensions Management Ltd 25,000 0.00735 Direct Sun Life Unit Assurance Ltd 53,913 0.01585 FTSE All Share Tracker Direct Sun Life Pensions Management 294,874 0.08668 FTSE All Share Tracker Direct AXA Framlington 750,000 0.22046 SEI UK Equity Indirect AXA Framlington 1,600,000 0.47031 St James Place Exempt (Pens) Fund Indirect AXA Framlington 1,800,000 0.52910 St James Place Net (Life) Fund Indirect AXA Framlington 400,000 0.11758 St James Place Offshore Fund Indirect AXA Framlington 600,000 0.17637 Daimler Chrysler Indirect AXA Framlington 3,120,333 0.91720 Throgmorton Trust Indirect AXA Framlington 15,013,453 4.41308 UK Select Ops Indirect AXA Framlington 13,753,131 4.04262 Equity Income Indirect AXA Framlington 2,000,000 0.58788 Managed Balanced Indirect AXA Framlington 1,500,000 0.44091 UK Smaller Companies Indirect AXA Framlington 500,000 0.14697 BAE Systems Pensions Fund CIF Trustees Indirect AXA Framlington 220,000 0.06467 BAE Systems 2000 Pensions Fund Indirect Framlington onshore private clients 6,820,157 2.00473 Indirect Axa Sun Life With Profits Passive 226,817 0.06667 Direct Sun Life Ass With Profits Passive 141,062 0.04146 Direct AXA Framlington St James Place Internal Equity & Income UT 225,000 0.06614 Indirect Total Direct 741,666 0.21801 Total Indirect 48,854,003 14.36024 TOTAL 49,595,669 14.57825 Proxy Voting: 9. Name of the proxy holder: 10. Number of voting rights proxy holder will cease to hold: 11. Date on which proxy holder will cease to hold voting rights: 12. Additional information: | Ends | For further information please contact: Protherics Nick Staples, Director of Corporate Affairs +44 (0) 7919 480510 Julie Vickers, Company Secretary +44 (0)1928 518010 Financial Dynamics - press enquiries London: Ben Atwell, Lara Mott +44 (0) 20 7831 3113 New York: John Capodanno, Jonathan Birt +1 212 850 5600 Or visit www.protherics.com This information is provided by RNS The company news service from the London Stock Exchange END
Protherics PLC - Notification of Major Interests in Shares
| Source: Protherics PLC
Cheshire, UK--(Marketwire - December 21, 2007) -