SOURCE: OR-Live, Inc.

January 17, 2008 07:15 ET

REMINDER: ORLive Presents: Leading Cardiac Surgeons Demonstrate Breakthrough Device to Facilitate Beating Heart and Robotic Coronary Revascularization Surgery

Live Webcast: From The Wisconsin Heart Hospital in Milwaukee: January 17, at 3:00 p.m. Eastern Time

REDWOOD CITY, CA--(Marketwire - January 17, 2008) - Cardica, Inc. (NASDAQ: CRDC) today announced that leading cardiac surgeons from The Wisconsin Heart Hospital and Centennial Medical Center in Nashville will webcast a live off-pump coronary artery bypass graft (CABG) procedure as well as a recently taped port-access robotic CABG procedure using innovative anastomotic devices from Cardica, Inc. The approximately 75-minute live webcast will be available on www.OR-Live.com on Thursday, January 17, at 3:00 p.m. Eastern Time to medical professionals. A replay will be available for 180 days following the live presentation to interested parties.

During the webcast, Husam H. Balkhy, M.D., chairman of the department of cardiac surgery of The Wisconsin Heart Hospital, will perform a beating heart procedure using Cardica's C-Port xA® and C-Port® Flex A™ Distal Anastomosis Systems. The innovative C-Port anastomosis systems are designed to allow surgeons to automate the attachment of blood vessel grafts, replacing traditional hand-sewn sutures.

In addition to the live surgery, Louis A. (Trey) Brunsting III, M.D., cardiothoracic surgeon at Centennial Medical Center in Nashville, will present recently taped video footage that shows a robotic closed-chest bypass procedure using the C-Port Flex A system in combination with the Intuitive da Vinci® Surgical System. This procedure was done on a 56-year-old male patient with a blockage of his left anterior descending and diagonal vessels. To date, Dr. Brunsting has performed several closed-chest procedures using the Cardica device.

Tung H. Cai, M.D., medical director and chief of cardiothoracic surgery at the Presbyterian Hospital of Denton, Texas, also will review his publication of data regarding patency of saphenous vein graft connections using the C-Port system and discuss Dr. Balkhy's recent presentation at the American Heart Association Scientific Sessions evaluating the patency of bypass grafts connecting the IMA to the left anterior descending (LAD) artery using C-Port systems during beating heart CABG surgery. We believe this particular type of bypass is vital to the development of robotic, closed-chest bypass procedures, and therefore proving its efficacy in open-chest procedures is critical.

Drs. Brunsting and Cai will narrate during the procedures, explaining critical aspects of the surgery, and will answer viewers' email questions.

According to Dr. Balkhy, "Cardica's C-Port systems represent a breakthrough in distal anastomotic devices that facilitate and simplify beating heart and robotic CABG procedures. These devices allow surgeons to offer patients less invasive cardiac surgery and may improve outcomes. This live webcast will provide surgeons with a convenient forum for an interactive exchange of questions, ideas and opinions about these revolutionary devices."

"The C-Port Flex A system has the potential to revolutionize the field of cardiothoracic surgery, as it may enable closed-chest, robot-assisted CABG procedures to be more reliably performed without the assistance of cardiopulmonary bypass and cardioplegic arrest of the heart," added Dr. Brunsting.

This OR-Live broadcast will be limited to medical professionals to comply with the Society of Thoracic Surgeons guideline not to televise live surgery to the general public. Medical professionals can register for the live broadcast at http://www.or-live.com/Cardica/2201. Other interested parties are invited to view the archived webcast that will be available the following day.

In addition to the January 17, 2008 broadcast, a second OR-Live event, sponsored by the Genesis Medical Center in Davenport, Iowa, will be held on February 5 at 7:00 p.m. CST, and also will focus on the C-Port system's ability to facilitate off-pump CABG.

About the C-Port xA and Flex A Anastomosis Systems

Cardica's C-Port systems are designed to enable automated, reliable and reproducible connections of blood vessels during CABG surgery. Unlike most hand-sewn anastomoses, Cardica's C-Port systems create compliant anastomoses that can expand and contract with blood flow. In addition, the C-Port anastomosis systems, whether used during on- or off-pump surgery, offer surgeons unique access to a wide range of coronary arteries, particularly small coronary arteries on which, in the past, CABG procedures have been very difficult or impossible to perform. The C-Port Flex A system features several innovative modifications to Cardica's C-Port xA system. The C-Port Flex A system has a flexible, rather than rigid, shaft and is designed to create compliant anastomoses in vessels as small as one millimeter in internal diameter. Importantly, the flexible shaft is designed to allow surgeons to position the device to create a secure connection even in difficult to reach areas of the heart.

About The Wisconsin Heart Hospital

Located in Wauwatosa, Wisconsin, The Wisconsin Heart Hospital, a member of Wheaton Franciscan Healthcare, was the vision of a group of cardiac, vascular and specialty physicians who wanted to treat broad-based diseases that affect cardiac and vascular systems. They began with a unique premise -- they wanted to help shape the future of cardiovascular care through locating innovative workflow, patient care, diagnostics and imaging technologies under one roof.

The only cardiovascular specialty hospital and first accredited chest pain center in the Milwaukee area, the 60-bed hospital was designed for the complexities of heart and vascular care. Its services include diagnostic and interventional cardiac catheterization and peripheral vascular procedures, electrophysiology, surgical services, diagnostic imaging, emergency services and wellness and preventive medicine programs.

For more information about The Wisconsin Heart Hospital, its award-winning care and outstanding outcomes, log on to twhh.org or contact Mary McIntosh at 414-778-7810.

Centennial Heart Center

The Centennial Heart Center offers a full complement of cardiac care delivered by more than 50 cardiac specialists. Each year the heart center performs nearly 1,200 heart surgeries and almost 6,000 minimally invasive cardiac procedures. This total far exceeds the American Heart Association's (AHA) and the American College of Cardiology's recommendation that hospitals perform a minimum of 300 cases per year to ensure quality outcomes. Centennial Heart Center ranks among the top 10 percent of programs in the country by surgical volume. For more information, please visit www.centennialmedicalcenter.com

About Intuitive's Products:

The da Vinci® Surgical System consists of a surgeon's viewing and control console having an integrated, high-performance InSite® 3-D vision system, a patient-side cart consisting of three or four robotic arms that position and precisely maneuver endoscopic instruments and an endoscope, and a variety of articulating EndoWrist® Instruments. By integrating computer-enhanced technology with surgeons' technical skills, Intuitive believes that its system enables surgeons to perform better surgery in a manner never before experienced. The da Vinci® Surgical System seamlessly and directly translates the surgeon's natural hand, wrist and finger movements on instrument controls at the surgeon's console outside the patient's body into corresponding micro-movements of the instrument tips positioned inside the patient through small puncture incisions, or ports.

About Cardica

Cardica is a leading provider of automated anastomosis systems for coronary artery bypass graft (CABG) surgery. By replacing hand-sewn sutures with easy-to-use automated systems, Cardica's products provide cardiovascular surgeons with rapid, reliable and consistently reproducible anastomoses, or connections of blood vessels, often considered the most critical aspect of the CABG procedure. Cardica's C-Port® Distal Anastomosis Systems are marketed in Europe and the United States. The PAS-Port® Proximal Anastomosis System is marketed in Europe and Japan and is being evaluated in a pivotal trial in the United States and Europe. Cardica also is developing additional devices with Cook Incorporated to facilitate vascular closure and other surgical procedures.

Forward-Looking Statements

This press release contains "forward-looking" statements, including statements relating to the long-term viability of anastomoses created with C-Port systems and the impact the adoption of Cardica's C-Port systems on the future success of closed-chest CABG procedures. Any statements contained in this press release that are not historical facts may be deemed to be forward-looking statements. The words "believe," "may," "expect" and similar expressions are intended to identify forward-looking statements. There are a number of important factors that could cause Cardica's results to differ materially from those indicated by these forward-looking

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