SOURCE: Xtalks

Xtalks Webinars

May 02, 2017 08:26 ET

Alternatives to HTS - Hit-finding Approaches in the Medicinal Chemist's Arsenal, New Webinar Hosted by Xtalks

TORONTO, ON--(Marketwired - May 02, 2017) - In a live broadcast on Thursday, May 18, 2017, industry expert Dr. Sam Mann, Principal Scientist, Medicinal Chemistry from Charles River Laboratories will look at some of the complementary approaches to HTS from a chemist's perspective and how these strategies have been successfully applied to real drug discovery programs at Charles River for Charles River's partners.

Examples of such approaches include:

  • Knowledge-based design: using chemistry expertise to make inventive modifications to known bioactive molecules
  • In silico screening: using structure and ligand-based approaches to virtually screen large collections of compounds
  • Fragment screening via low-throughput biophysical techniques such as SPR and NMR

While high-throughput screening (HTS) remains a powerful weapon for hit identification, it is important to be aware of the many alternative tools available to the medicinal chemist for initiating a drug discovery program. No hit identification method is always fruitful; they all have their strengths and weaknesses, and only by judicious integration of hit identification approaches can the chances of success be maximized.

Learning Objectives

  • Better understand the range of alternative hit-finding approaches to HTS
  • Understand how these approaches can be complementary to each other
  • View case study examples of how each has been successfully applied to real drug discovery programs

For more information about this free webinar visit: Alternatives to HTS - Hit-finding Approaches in the Medicinal Chemist's Arsenal

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global Life Sciences community. Every year thousands of industry practitioners (from pharmaceutical & biotech companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit

For information about hosting a webinar visit

Image Available:

Contact Information