SOURCE: Appistry


April 23, 2013 09:28 ET

Appistry Announces Partnership With LifeMap Sciences, a Subsidiary of BioTime

Agreement Will Integrate Critical Sources of Genetic and Disease Information Into Appistry's Next-Generation Sequencing ("NGS") Reports for Clinicians

ST. LOUIS, MO--(Marketwired - April 23, 2013) -  Appistry, Inc., which provides a big-data computing environment that supports life-science and medical analytics and workflows, announced today a collaborative partnership and value-added reseller agreement with LifeMap Sciences, Inc., a subsidiary of BioTime, Inc. The intent of the partnership is to integrate LifeMap's GeneCards® and MalaCards databases of human genes and diseases into the outputs produced by genomics pipelines running on Appistry's Ayrris™ computing environment. Appistry will market sequence analysis outputs and reports that include the GeneCards® and MalaCards data to clinicians and researchers under a revenue share arrangement with LifeMap, based on sales of such reports.

Modern healthcare is increasingly dependent on genetic testing and molecular diagnostics, particularly as the costs associated with gene sequencing have dropped with the advent of next-generation sequencing (NGS) technologies. In fact, labs and hospitals cite analysis of NGS data as the primary bottleneck to leveraging genetic information to better diagnose disease, assess treatment options, and develop the targeted therapies that will enable personalized medicine.

"One of the biggest limitations on using next-generation sequencing in clinical settings is the ability to effectively translate raw sequence data into medically meaningful results," said Kevin Haar, CEO of Appistry. "To realize the promise of personalized medicine, organizations need to scale their bioinformatics pipelines to handle thousands of patient cases, while also providing information physicians can act on. Our partnership with LifeMap enables medical researchers to extend their analytic processes to deliver a better understanding of the biological pathways and disease states associated with genetic samples."

Appistry's Ayrris™ computing environment supports the rapid assembly of complex, data-intensive analytics that run a customer's choice of open-source, commercial, and proprietary tools at scale without requiring specialized expertise in high-performance computing or a complex software development effort. Under the partnership, Appistry will deliver access to data from LifeMap's GeneCards® and Malacards databases within the pipeline results and personalized medicine reports provided by its Ayrris™ life science solutions and services. GeneCards®, the human gene compendium, provides concise genomic information on all known and predicted human genes, including gene-disease associations, variants and single nucleotide polymorphisms, gene function and other fields of interest. MalaCards, the human disease database, contains information relating to a wide array of human diseases and the roles of genes in disease processes. LifeMap Sciences holds the exclusive worldwide license to market GeneCards® and MalaCards from Yeda Research and Development Company Ltd., the commercial arm of the Weizmann Institute of Science.

"We expect LifeMap Sciences to be the leading source of gene and disease information for clinicians and patients in the rapidly growing fields of molecular diagnostics, prevention and personalized medicine," said David Warshawsky, Ph.D., CEO of LifeMap. "The combination of GeneCards® and MalaCards comprehensive gene and disease related knowledge with the end-to-end NGS analysis workflow offered by Appistry will greatly enhance the potential for improved diagnosis, prevention, and treatment of devastating conditions."

About Appistry

Appistry ( orchestrates solutions to big data problems, and since 2001, the company's fabric technology has empowered organizations and researchers to transform vast data into actionable intelligence. Appistry weaves together high-performance computing and analytics to provide the throughput and scale required for diverse applications -- from discovering new medical therapies to delivering overnight packages, gaining clarity from financial transactions, or deciphering military satellite images. In 2012, Appistry was selected by the Broad Institute as the exclusive distributor of the GATK for use in for-profit settings. 

About LifeMap Sciences, Inc.

LifeMap Sciences' ( core technology and business is based on its integrated database suite, which includes GeneCards®, the leading human gene database; LifeMap Discovery™, the database of embryonic development, stem cell research and regenerative medicine; and MalaCards, the human disease database. According to Google Analytics, the sites have generated more than 2,000,000 unique visitors with more than 13,000,000 page views in the past 12 months. LifeMap is BioTime's principal internet marketing subsidiary for research products, including PureStem™ human progenitor cell lines. In a therapeutic discovery collaboration with BioTime, LifeMap's scientists utilize LifeMap's proprietary platform to aid in the development of BioTime's proprietary PureStem™ cell lines into products for the treatment of human diseases. 

Contact Information

  • Media Contacts

    Deborah Ausman
    Director, Marketing Communications
    Appistry, Inc.

    Kenneth Elsner
    Chief Operating Officer
    LifeMap Sciences, Inc.