Applied DNA Sciences, Inc. Migrates to the OTCQB Tier of the OTC Marketplace


STONY BROOK, NY--(Marketwire - March 8, 2011) - Applied DNA Sciences, Inc. (OTCQB: APDN) announced that it has migrated from the OTCBB quotation and trading system to the OTC Markets Group Inc. quotation and trading system -- APDN's stock is now quoted on the OTC Markets (www.otcmarkets.com/stock/apdn/quote) OTCQB tier. OTC Markets provides free level II real time quotes.

This change was caused as a result of a large migration of brokers from the OTCBB quotation system to the OTC Markets quotation system. OTC Markets provides an electronic platform contrary to the OTCBB quotation system which continues to operate on a telephonic trading platform. This change was not caused by any action or inaction by APDN. APDN continues to be in full compliance with all of its reporting requirements. According to otcmarkets.com, in the past 30 calendar days, there have been 837 publicly traded companies that have moved from being dually quoted (OTCBB and OTC Link) to being quoted exclusively on the OTC Link platform. As of the end of last week, priced quotes published on OTC Link made up 95% of priced quotes in the OTC marketplace. This movement shows brokers' continued support of the electronic OTC Link system, as they migrate to quote exclusively on this platform.

Trading information for APDN may take a while to be updated in some trading platforms and quotation systems. For current stock quotes for APDN, investors can always go to the www.otcmarkets.com website to stay current on APDN's trading activity and stock price.

About OTC Markets Group, Inc.
OTC Markets Group Inc. operates the world's largest electronic marketplace for broker-dealers to trade unlisted stocks. Our OTC Link platform supports an open network of competing broker-dealers that provide investors with the best prices in over 10,000 OTC securities. In 2010, securities on OTC Link traded over $144 billion in dollar volume, making it the third largest U.S. equity-trading venue, after NASDAQ and the NYSE. We categorize the wide spectrum of OTC-traded companies into three tiers -- OTCQX (the quality-controlled marketplace for investor friendly companies), OTCQB (the U.S. reporting company marketplace for development stage companies), and OTC Pink (the speculative trading marketplace) -- so investors can identify the level and quality of information companies provide. To learn more about how OTC Markets Group, Inc. makes the unlisted markets more transparent, informed and efficient, visit www.otcmarkets.com.

About APDN
APDN sells patented DNA security solutions that provide anti-counterfeit protection, as well as protecting brands and intellectual property from counterfeiting and diversion. SigNature DNA is a botanical mark used for product authentication in a unique manner that essentially cannot be copied. When used in conjunction with other law enforcement technologies, SigNature DNA can provide a forensic chain of evidence that has been used successfully in more than 15 convictions. To learn more, go to www.adnas.com where APDN routinely posts all press releases.

The statements made by APDN may be forward-looking in nature and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements describe APDN's future plans, projections, strategies and expectations, and are based on assumptions and involve a number of risks and uncertainties, many of which are beyond the control of APDN. Actual results could differ materially from those projected due to our short operating history, limited financial resources, limited market acceptance, market competition and various other factors detailed from time to time in APDN's SEC reports and filings, including our Annual Report on Form 10-K, filed on December 15, 2010 and our subsequent quarterly reports on Form 10-Q. APDN undertakes no obligation to update publicly any forward-looking statements to reflect new information, events or circumstances after the date hereof to reflect the occurrence of unanticipated events.

Contact Information:

INVESTOR CONTACT:
Debbie Bailey
631-444-8090
fax: 631-444-8848

MEDIA CONTACT:
Janice Meraglia
631-444-6293
fax: 631-444-8848

FCMN Contact:

Web site: http://www.adnas.com