SOURCE: Xtalks

Xtalks Webinars

August 25, 2015 07:00 ET

Applying Tissue Phenomics® to Clinical Questions for Patient Stratification, New Webinar Hosted by Xtalks

TORONTO, ON--(Marketwired - August 25, 2015) - During a live webinar on September 23, 2015, esteemed speaker Dr. Peter Caie, Senior Research Fellow in Quantitative and Systems Pathology at University of St Andrews, will show how Tissue Phenomics® can be utilized to identify previously undiscovered prognostic and predictive image-based features or combinations of features for patient stratification. These features may have remained unreported due to being too subtle or complex to identify or quantify by eye or due to high observer variability. Upon collation of the hierarchical big data across patient samples it must be mined in order to distill the most significant parameters to answer the clinical question and create a transferable test.

Dr. Caie will walk through:

  • How Tissue Phenomics® can be utilized to identify heterogeneous subpopulations within a patient sample. These subpopulations can be further investigated through multi-omics approaches to better understand, for example, tumor heterogeneity and how this affects disease progression or response to treatment.
  • How Tissue Phenomics® has been applied to identify a novel histopathological feature, identified through the quantification of known and unbiasedly captured histopathological object features, capable of stratifying high risk stage II colorectal cancer patients.
  • How the novel histopathological feature was further integrated with other significant clinical pathology parameters to form a highly significant prognostic signature (HR = 7.8; 95% CI, 3.2 - 19.2).

Cutting edge image analysis software allows the hierarchical standardized and reproducible quantification of set histopathological features, cell types and biomarkers across a patient sample. Image analysis applied in this fashion has the ability to transform pathology from a subjective and semi-quantitative field into a fully objective and quantitative one. Image analysis of digital pathology specimens, like the more classical 'omics' fields, now has the ability to create robust big data. The capture and mining of this data, which can be comprised of set histopathological features, unbiasedly collected image parameters and their spatial heterogeneity, has been termed Tissue Phenomics®.

There are two live broadcasts scheduled on Wednesday, September 23, 2015, at 2pm BST (UK/GMT +1), and 1pm EDT. To learn more about this event visit: Applying Tissue Phenomics® to Clinical Questions for Patient Stratification

Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global Life Sciences community. Every year thousands of industry practitioners (from pharmaceutical & biotech companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

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