Contact Information: CONTACT: Ann Elsas The Ledlie Group for EARTH University Foundation 404.266.8833 Tracie Ingram Earth University Foundation 404-995-1235 WEB SITE: http://www.earth-usa.org/ http://www.earth.ac.cr/index.php
Atlanta's EARTH University Foundation Gets Anonymous Donation to Fight Chagas Disease
Supportive Donor Gives $300,000 to Project Aimed at Finding a Cure for Chagas Disease
| Source: EARTH University Foundation
ATLANTA, GA--(Marketwire - January 29, 2008) - Ewire -- Atlanta-based EARTH University
Foundation announced today that it has received $300,000 from a very
supportive donor, who wishes to remain anonymous, to fund research over the
next two years to find a cure for Chagas disease.
Chagas disease is the most prominent parasitic disease in Latin America. It
affects an estimated eight to 11 million people in rural areas in the
southern United States, Mexico, Central America and South America and,
according to the Centers for Disease Control and Prevention, is estimated
to cause approximately 50,000 deaths worldwide each year. Researchers say
the U.S. could be housing more than 100,000 people with Chagas disease who
were infected while living in Latin America.
Thanks to the donation, enhanced research toward finding a cure will be
carried out by professors at EARTH University in Costa Rica and by
scientists at two additional institutions in a consortium called ChagaSpace
Project. ChagaSpace (www.chagaspace.org) is a joint project between NASA,
and several universities and institutions, with EARTH University serving as
the research coordinating entity. Established in 1995, ChagaSpace
researchers are working together to find a cure for Chagas disease by
utilizing the biological diversity of the humid tropics and by conducting
crystallization processes in space.
ChagaSpace researcher and former astronaut Dr. Franklin Chang-Díaz explains
space's role in the research, saying, "The absence of gravity makes it
easier to conduct crystallization processes. In fact, zero gravity is the
ideal environment for the crystallization of proteins [and using this
method] it's easier to study the molecular structure of the substances that
inhibit the parasite's activities."
After 13 years of work and a concentrated effort to decode the disease in
space, the results are promising: the team has crystallized three enzymes
with the potential to neutralize the parasite that causes Chagas disease;
they have identified various natural blocking agents; and they are studying
the possibility of cleaning contaminated blood with a plant extract.
The next round of research, courtesy of the donor's $300,000 gift, will
focus on the preservation of biodiversity in the tropics. Extracts from the
biota of the tropics will be used to find the molecular "locks" on the
enzymes in T. cruzi, the parasite that causes Chagas disease. The project
combines space protein crystallography techniques with the search and
potential use of natural extracts from tropical forests to develop blocking
agents and to help conserve rainforest biodiversity by stressing
non-destructive use of it. EARTH University's partner institutions for this
unique track of research include the Institute for Biodiversity in Costa
Rica and the University of Alabama at Birmingham.
"This phase of the endeavor, made possible in part by the donor's gift, is
an exciting venture, as it marks further progress in the first
collaborative medical space project undertaken at the level of the whole
American continent," said Dr. Bert Kohlmann, professor and Director of
Research at EARTH University. "All of the team members at ChagaSpace are
grateful for this valuable opportunity to sharpen our techniques and
continue our efforts in finding a cure for this deadly disease."
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http://www.ewire.com/display.cfm/Wire_ID/4496