biOasis Technologies Inc.

biOasis Technologies Inc.

May 27, 2015 09:00 ET

biOasis Enters Into A Collaborative Research and Joint Funding Support Agreement Entitled "Focus on Brain"

VANCOUVER, BRITISH COLUMBIA--(Marketwired - May 27, 2015) - biOasis (TSX VENTURE:BTI)(OTCQX:BIOAF) today announces that it, in partnership with the National Research Council of Canada and the Université de Sherbrooke, has been awarded a collaborative research grant by the CQDM and Brain Canada. In their "Focus on Brain" call for proposals, the partners received a number of applications from companies and academic institutions. The focus of the research agreement is to identify a new generation of potential blood-brain barrier (BBB) carrier molecules.

Mr. Rob Hutchison, Principal Investigator, will lead the three teams located at; the National Research Council of Canada (NRC), Dr. Danica Stanimirovic MD, PhD; the Université de Sherbrooke, Dr. Brigitte Guérin; and the biOasis research team. The research funding, as announced by CQDM, $2,573,875 over 3 years, comes from CQDM and Brain Canada, with co-investment (in-kind) from NRC. The primary goal of the project is to develop a platform of blood-brain carriers and evaluate them preclinically. The foundational work will be conducted at NRC, beginning with the isolation of lead blood-brain barrier carriers from an NRC library of human single domain antibodies. Together with the Université de Sherbrooke and biOasis, the research teams will validate potential candidates using in vivo imaging and will conduct comparative studies against known carriers such as biOasis's Transcend.

The project team brings together leaders in the fields of domain antibody engineering (NRC), blood-brain barrier R&D (biOasis, NRC) and in vivo translational imaging (Université de Sherbrooke). The overall project goal is to transfer new brain delivery technology to biOasis for commercial development through licensing agreements with major pharmaceutical companies.

Mr. Rob Hutchison, the CEO of biOasis, commented, "When we became aware of the Focus on Brain program launched by CQDM in partnership with Brain Canada and the Ontario Brain Institute, it was clear to us that biOasis needed to be a part of it, as our central mandate is focused on the delivery of therapeutics to the brain. We've successfully developed our Transcend technology with this goal in mind and now this new collaboration with expert partners represents a wonderful opportunity to expand our BBB carrier platform. Our expert team that developed Transcend will play a significant role in this project, which will enhance our current Transcend offering by expanding the BBB transports that we will be able to provide to our future partners."

About Transcend

Transcend is biOasis' proprietary platform for the delivery of therapeutics across the BBB to address unmet medical needs in the treatment of central nervous system diseases such as; metastatic and other forms of brain cancers, neurodegenerative and metabolic diseases. The BBB represents the single greatest challenge in treating neurological disorders. The ability to effectively and safely breech the BBB offers the opportunity for biOasis to deliver therapeutics into the brain. Transcend was originally based on MTf (melanotransferrin or P97) where the full-length protein was conjugated to therapeutic molecules. Recently biOasis identified a family of peptides within MTf that facilitates receptor mediated transcytosis.

About biOasis

biOasis Technologies Inc. is a biopharmaceutical company headquartered in Vancouver, Canada focused on overcoming the limitations of therapeutic drug delivery across the BBB. The company is developing and commercializing a proprietary brain delivery technology to address unmet medical needs in the treatment of central nervous system disorders. biOasis trades on the OTCQX under the symbol "BIOAF" and on the TSX Venture Exchange under the symbol "BTI". For more information about the company please visit

Forward Looking Statements

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On Behalf of the Board of Directors

Rob Hutchison, Chairman & CEO

"Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release"

Contact Information

  • biOasis Technologies Inc.
    Corporate: Mr. Rob Hutchison 1-778-383-3280
    Scientific: Dr. Reinhard Gabathuler 1 (514) 963-6177