SOURCE: Northwell Health

Northwell Health

June 16, 2016 14:40 ET

Clinical Trial to Repair Damaged Heart Muscle With Cardiac Stem Cells Currently Underway at Lenox Hill Hospital

NEW YORK, NY--(Marketwired - June 16, 2016) - A revolutionary new trial brings hope to the 735,000 Americans who suffer from heart attacks each year. Lenox Hill Hospital researchers are taking part in a national trial investigating whether damaged heart tissue can be safely and effectively regenerated with the help of adult cardiac stem cells. The hospital, which is the only site in the tri-state area conducting this research, is currently recruiting participants who have sustained moderate to severe heart damage due to a heart attack within the past year.

The "ALLSTAR" (ALLogenic Heart STem Cells to Achieve Myocardial Regeneration) trial, currently in its second stage, is sponsored by Capricor Therapeutics, Inc., a clinical-stage biotechnology company specializing in developing cardiac therapies. Lenox Hill Hospital is investigating whether heart-derived adult stem cells directly infused into the area affected by a heart attack can repair heart muscle that has been damaged or has died, as a result of a heart attack. The infusion contains Capricor's proprietary off-the-shelf stem cell product, CAP-1002, that is derived from donor heart tissue.

"This groundbreaking trial could provide us with the breakthrough we have been searching for for many years. A positive outcome would be a game-changer," said Varinder Singh, MD, chairman of cardiovascular medicine at Lenox Hill Hospital and site principal investigator. "The ability to essentially heal impaired and dead cardiac tissue would improve not just the odds of survival but could significantly enhance the quality of life for heart attack survivors."

According to the CDC, every 43 seconds, someone in the U.S. experiences a heart attack. A heart attack occurs when a part of the heart muscle does not receive adequate blood flow. As a result, the affected cardiac tissue dies, weakening that particular area of the heart and preventing the heart muscle from pumping blood as efficiently. The more time that passes without treatment to restore blood flow, the greater the damage to the heart muscle. This damage may lead to congestive heart failure, a leading cause of death and disability in the U.S. Approximately half of all people who develop heart failure die within five years of diagnosis.

The ALLSTAR trial is being conducted at 32 medical centers across the country with Lenox Hill being one of only two locations in New York State, and the sole site within New York City and the tri-state area.

For more information on this trial, please contact Priscilla Chu at (212) 212-434-3362 or visit http://1.usa.gov/1UvcpsQ .

About Lenox Hill Hospital
Lenox Hill Hospital, a member of Northwell Health, is a 652-bed, fully accredited, acute care hospital located on Manhattan's Upper East Side with a national reputation for outstanding patient care and innovative medical and surgical treatments. US News & World Report has ranked the hospital among the nation's top 50 in Cardiology and Heart Surgery and among the top 10 hospitals in the state of New York with a total of 11 "high performing" designations for its clinical performance in Cancer, Diabetes & Endocrinology, Ear, Nose & Throat, Gastroenterology & GI Surgery, Geriatrics, Gynecology, Nephrology, Neurology & Neurosurgery, Orthopedics, Pulmonology and Urology. For more information, go to www.lenoxhillhospital.org.

About Northwell Health
Northwell Health (formerly North Shore-LIJ Health System) is New York State's largest health care provider and private employer. With 21 hospitals and nearly 450 outpatient practices, we serve more than 1.8 million people annually in the metro New York area and beyond. Our 61,000 employees work to change health care for the better. We're making breakthroughs in medicine at the Feinstein Institute. We're training the next generation of medical professionals at the visionary Hofstra Northwell School of Medicine and the School of Graduate Nursing and Physician Assistant Studies. And we offer health insurance through CareConnect. For information on our services in more than 100 medical specialties, visit Northwell.edu.

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