SOURCE: Xtalks

Xtalks Webinars

September 11, 2014 07:05 ET

Comparative Placental Transfer of Biologics: Preclinical Alternatives to the Nonhuman Primate, Live Webinar Hosted by Xtalks

TORONTO, ON--(Marketwired - September 11, 2014) - This webinar will provide the latest information concerning mAb placental transfer, including human IgG1 in the mouse, comparing results to other laboratory species such as rats and minipigs. The live broadcast will take place on Wednesday, September 24, 2014 at 9am EDT (NA) / 2pm BST (UK GMT +1).

Understanding the placental transfer of biologics has traditionally involved studies with nonhuman primates. However, other animal models may be viable alternatives.

Unlike small molecule drugs, large molecule biopharmaceuticals do not undergo placental transfer by simple diffusion and can therefore offer reduced risk of exposure to the developing embryo and fetus. Antibody-like biopharmaceuticals, however, undergo placental transfer utilizing a receptor-mediated mechanism used for the transport of maternal antibodies to the conceptus. Binding to fetal targets has the potential to adversely affect development.

This session featuring presenters from WIL Research and Exponent, will provide the latest information concerning mAb placental transfer, including human IgG1 in the mouse, comparing results to other laboratory species such as rats and minipigs. The discussion will seek to put into perspective the relevance of using these animal models during the development of antibody-like biotherapeutics.

For more information or to register for this webinar, visit: Comparative Placental Transfer of Biologics: Preclinical Alternatives to the Nonhuman Primate

About Xtalks
Xtalks, powered by Honeycomb Worldwide Inc., is a leading provider of educational webinars to the global Life Sciences community. Every year thousands of industry practitioners (from pharmaceutical & biotech companies, private & academic research institutions, healthcare centers, etc.) turn to Xtalks for access to quality content. Xtalks helps Life Science professionals stay current with industry developments, trends and regulations. Xtalks webinars also provide perspectives on key issues from top industry thought leaders and service providers.

To learn more about Xtalks visit http://xtalks.com
For information about hosting a webinar visit http://xtalks.com/sponsorship.ashx

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Contact Information

  • Contact:
    Michelle Tran
    Tel: +1 (416) 977-6555 ext 352
    Email: mtran(at)xtalks(dot)com