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Daxor Announces Publication of Clinical Study Demonstrating Blood Volume Analysis Benefits Critically Ill Surgical Patients
| Source: Daxor Corp.
NEW YORK, NY--(Marketwire - March 17, 2008) - Daxor Corporation (AMEX : DXR ), a medical
instrumentation and biotechnology company, today announced the publication
in the Hawaii Medical Journal of "Circulating Blood Volume Measurements
Correlate Poorly with Pulmonary Artery Catheter Measurements," which
demonstrated clinical benefit of the Blood Volume Analyzer BVA-100 to
critically ill surgical patients.
In this pilot study, twenty critically ill surgical intensive care unit
(SICU) patients who had been admitted to Queen's Medical Center, Honolulu,
HI, had their fluid management treatment changed 21% of the time due to
Daxor's Blood Volume Analyzer. Treatment changes resulted in patients
experiencing clinical improvements in cardiac, pulmonary and/or kidney
function.
The Queen's SICU medical team was asked to determine patient volume status
by conventional parameters such as pulmonary artery catheter (PAC)
measurements and Blood Volume Analysis (BVA) with Daxor's Blood Volume
Analyzer BVA-100. The BVA results were utilized to guide fluid management
therapy. The BVA altered treatment was compared to conventional surrogate
methods to discover if patients benefited from the BVA guided treatment.
Prior to BVA, fluid management in the SICU has historically been based on
surrogate measurements like the PAC despite data from several previous
clinical trials showing that the PAC is a poor reflection of a patient's
response to fluids. In this study, the PAC showed weak statistical
agreement with BVA.
The patients in this study had respiratory failure, severe septic shock and
hemorrhagic shock. Diagnosing and treating intravascular blood volume in
these patients is critical. The investigators of this study noted that,
"Measuring pressure to infer volume continues to be problematic.
Furthermore, circulating BVA provides distinct measurement of disturbances
in the red blood cell volume and the plasma volume. This precise
information, resulting in treatment targeted at improving each individual
component of total blood volume, is not obtainable from pressure
measurements provided by the pulmonary artery catheter."
Additional larger studies are on-going at Queen's Medical Center and other
medical institutions to further demonstrate clinical efficacy of a BVA in
critically ill and other chronic and acute medical conditions.
Daxor Corporation manufactures and markets the BVA-100, the only
FDA-approved semi-automated Blood Volume Analyzer. The BVA-100 is used in
conjunction with Volumex, Daxor's single use diagnostic kit. For more
information regarding Daxor Corporation's Blood Volume Analyzer BVA-100,
visit Daxor's website www.Daxor.com.