SOURCE: Earth Science Tech, Inc.

April 13, 2015 08:00 ET

ETST and DV Biologics Begin Testing ETST CBD (Cannabidiol) Rich Hemp Oil In Vitro on Various Human Primary Cells to See if it Serves as a Neuroprotectant Which May Help With Neurodegenerative Disorders Such as Alzheimer's and Parkinson's Disease

BOCA RATON, FL--(Marketwired - April 13, 2015) - Earth Science Tech, Inc. (OTCQB: ETST) ("ETST" or "the Company"), a unique biotechnology company focused on nutraceuticals, bioceuticals and dietary supplements, announced today that DV Biologics, a leading biological company, has begun third party testing on ETST High Grade CBD (Cannabidiol) Rich Hemp Oil in vitro on various human primary cells. DV Biologics has identified it will be testing if ETST High Grade CBD (Cannabidiol) Rich Hemp Oil serves as a neuroprotectant which may help with neurodegenerative disorders such as Alzheimer's and Parkinson's disease.

In order to assure the world that ETST produces the best products with scientific support, ETST has engaged the expertise of a leading independent biological company, DV Biologics LLC, to test ETST High Grade CBD (Cannabidiol) Rich Hemp Oil in vitro on various human primary cells. Using human primary cells will give ETST a better scientific understanding of what ETST High Grade CBD (Cannabidiol) Rich Hemp Oil is most beneficial for. To commence, DV Biologics has specified it will be testing if ETST High Grade CBD (Cannabidiol) Rich Hemp Oil serves as a neuroprotectant which may help with neurodegenerative disorders such as Alzheimer's and Parkinson's disease. Specifically, ETST with the help of DV Biologics will look at the role of its CBD Hemp Oil and reactive oxygen species in the brain.

"We are excited to work with DV Biologics as they have many human cell based models that can demonstrate what our High Grade CBD (Cannabidiol) Rich Hemp Oil does to different cell types in our body. We want the public to know that we are focused on providing the best CBD with scientific studies that validate our products use," stated Dr. Harvey Katz, CEO of ETST.

"We are excited to work with ETST CBD (Cannabidiol) Rich Hemp Oil. There are many therapeutic purposes for this oil and we look forward to studying the characteristics of CBD in vitro with our human primary cell models which more closely resemble the human condition," stated Dr Rafael Gonzalez, VP of Research & Development for DV Biologics. 

ETST would like to let the market know the key advantage of in vitro work is that it simplifies the system under study, so that the investigator can focus on a small number of components. Another advantage of in vitro procedures is that human cells can be used directly therefore no translation from animal to human is needed in that circumstance. In vitro testing is also rather useful in the characterization of some precise metabolism, distribution, adsorption and excretion processes taking place inside the living organism. However, further experiments, particularly in vivo studies, will be needed to determine the ultimate effects of CBD Rich Hemp Oil serving as a neuroprotectant.

ETST invites all interested parties to contact the company at info@earthsciencetech.com in regards to securing its "High Grade CBD (Cannabidiol) Rich Hemp Oil" in bulk for wholesale, resale, private labeling or distribution. ETST is always open to forming new strategic partnerships, joint ventures and/or supplying vendors, resellers and third party distribution companies with its High Grade CBD Rich Hemp Oil at wholesale prices in order to better help supply consumers as well as the health and wellness markets on a large scale. Furthermore, you can view, research and purchase small quantities or bottles of ETST High Grade CBD (Cannabidiol) Rich Hemp Oil at www.earthsciencetech.com/cbd-rich-hemp-oil. 

ETST High Grade CBD (Cannabidiol) Rich Hemp Oil: ETST High Grade CBD (Cannabidiol) Rich Hemp Oil is all-natural, organic and formulated using a wide array of cutting-edge technologies. ETST is capable of supplying and offering its High Grade CBD Rich Hemp Oil in all 50 states and over 40 countries as a nutritional and dietary supplement designed to support overall wellness. ETST's High Grade CBD Rich Hemp Oil is all-natural and derived completely from the federally legal industrial hemp plant. Industrial Hemp (Hemp) is not marijuana and will not get you 'high' and it does not require a medical license of any kind to authorize purchase. It is lab tested multiple times during the manufacturing process, from seed to shelf. This also includes being tested for CBD content, other Cannabinoid content, yeast/mold/fungus, and bacteria like E. coli to ensure safety and top quality. Cannabidiol (CBD) is a naturally occurring constituent of the hemp plant. ETST believes that CBD Rich Hemp Oil awareness today is where Omega 3 and Omega 6 fatty acids were 15 to 20 years ago. ETST goal is to help consumers Worldwide with their overall wellness through advanced formulations with its CBD Rich Hemp Oil and cutting edge nutraceuticals and dietary supplements. CBD Rich Hemp Oil is posed to be the most renowned and effective natural compound and botanical alternative introduced to the nutritional and dietary supplement industry in decades. ETST plans on continuing its research, tests and clinical studies with the University of Central Oklahoma as well as other 3rd party labs in regards to its ETST High Grade CBD Rich Hemp Oil. Consumers worldwide desperately need more effective safe botanical alternatives to help them with their overall health and internal wellness. Modern science has identified over 400 phytonutrients in various parts of the industrial hemp plant. These include hundreds of Terpenoids, Essential Oils and Antioxidants but perhaps the most dynamic are a group of 80 compounds called Cannabinoids that are exclusively found in Hemp and one other place; our bodies. ETST CBD Rich Hemp Oil contains the synergistic Cannabinoids, Terpenoids, Essential Oils and other compounds found in the industrial hemp plant. There are roughly 80 different phyto-cannabinoids, most prominently CBD, CBC, CBG, CBN, and most likely others yet to be effectively identified. In addition to the cannabinoids present in our full spectrum raw industrial hemp oil extracts, there are also many other types of natural molecules and phyto-chemical compounds such as amino acids, sugars, vitamins, fatty acids (including omega 3 & 6), flavanoids, ketones, nitrogenous compounds, alkanes, alcohols, glycosides, pigments, hemp seed oil, water, and terpenes. The most common terpenes in our CBD oils are Beta-caryophyllene, Caryophyllene Oxide, Myrcene, Terpinolene, α Bisabolol, α Pinene, Nerolidol, Ocimene and Phytol. Hemp oil contains more essential fatty acids than any other plant.

Humans are designed with a built-in Endocannabinoid System (ECS). Research shows that many scientists believe cannabinoids work synergistically to support the whole human endo-cannabinoid system (internal and natural human cannabinoid system). It is your body's way of communicating with itself and properly regulating the way every other body system functions from your brain to your toes. The Endocannabinoid System (ECS) has shown to control pain sensation, appetite, temperature regulation, stress reactivity, immune function, and sleep as well as other processes. Even more interesting is that muscle and fat tissue also utilize these receptors to control their processes. Consumers should think of the Endocannabinoid System as one of the body's main control and command centers for tweaking your metabolism's ability to react and adapt to the world around it. Like many other nutrients in our diet, Cannabinoids can become exhausted and in need of steady dietary replenishment. Scientific studies and data show that CBD (Cannabidiol) Rich Hemp Oil as well as all micronutrients (phytonutrients) and phyto-cannabinoids found in the oil work in harmony with the human body's own endocannabinoid system making a positive effect for overall wellness. Hemp oil contains CBD -- a non-psychoactive compound of the plant. There are millions of hemp oil consumers around the world and this number is rapidly rising with an increasing number of reports and studies showing a variety of benefits of hemp oil.

Previous highlights on ETST High Grade CBD Rich Hemp Oil with the University of Central Oklahoma and its lead investigator Dr. Wei R. Chen: On October 9, 2014 ETST announced positive preliminary test results on the effects of ETST Hemp Oil Enriched with CBD-Cannabidiol on Animal Breast Cancer Cells and on Normal Cells. ETST had previously announced that the initial report from the Sponsored Research Agreement with the University of Central Oklahoma and its lead investigator Dr. Wei R. Chen showed the effects of its Hemp Oil Enriched with CBD-Cannabidiol (provided by Earth Science Tech, Inc.) on animal breast cancer cells and on normal cells. The results of this preliminary study indicate that with appropriate dose, in this case with ETST proprietary Hemp Oil Enriched with CBD-Cannabidiol dose, Hemp Oil Enriched with CBD-Cannabidiol can inhibit the proliferation of cancer cells more than that of normal cells. On October 20, 2014, ETST secured a New Provisional Patent for "Hemp Oil Enriched With CBD (Cannabidiol)" Filed with the United States Patent and Trademark Office (USPTO). ETST entered into an Assignment of Patent Application with Dr. Wei R. Chen for assignment of a patent pending under Application number 62061577 entitled "Cannabidols Composition and Uses Thereof." ETST has secured, and was assigned, this new patent for Hemp Oil Enriched with CBD (Cannabidiol) and Hemp Oil Enriched with Proprietary Additives. On January 16, 2015 ETST secured a Ground Breaking Second Provisional Patent for its CBD (Cannabidiol) Rich Hemp Oil Because of its Findings with the University of Central Oklahoma and the Effects of CBD on Immune Cells. Under the sponsorship of ETST, researchers at the University of Central Oklahoma have been investigating the effects of CBD on immune cells with ETST using the ETST CBD Rich Hemp OilETST would like to let the market and its shareholders know that this new patent (Patent Name is "Cannabidiol Compositions and Uses 2," Serial No. 62102538) was filed because of the positive ETST new findings under its sponsorship with the University of Central Oklahoma. These finding are breakthroughs in this field. With these new studies and test results, ETST has 2 provisional patents and inventions with its CBD Rich Hemp Oil (patent Serial No. 62102538 and patent Serial No. 62061577). Additionally, ETST has a total of ten (10) new claims for its Hemp Oil Enriched with CBD (Cannabidiol) and Hemp Oil Enriched with Proprietary Additives. Partial Abstract of new Patent Serial No. 62102538: A composition having cannabidiol, alone, or as a component of hemp oil, for use in treating or preventing cancer. The composition may include D-limonene, which contributes synergistically to the anticancer efficacy of the composition. On January 26, 2015 ETST announced Positive Test Results of its Product CBD (Cannabidiol) Rich Hemp Oil; In Collaboration with the University of Central Oklahoma, Test Results Demonstrate that CBD Rich Hemp Oil Enhances Immune Function. The results of this preliminary study indicate that with appropriate CBD concentrations, hemp oil can stimulate macrophages to produce TNF α and can also enhance the TNF α production stimulated by LPS. The study illustrated that ETST CBD Rich Hemp was capable of Stimulating and Enhancing Tumor Necrosis Factor alpha (TNFα) Production by Macrophages. Under the sponsorship of Earth Science Tech (ETST), researchers at the University of Central Oklahoma have been investigating the effects of CBD on immune cells with ETST using the ETST CBD Rich Hemp Oil. Led by lead investigator Dr. Wei R. Chen, the team found that ETST hemp oil solution used in appropriate CBD concentrations could stimulate macrophages, an important immune cell, through the production of TNF α. The cytokine TNF α is a key cell signaler in the recruitment of immune cells. Furthermore, they also found that the CBD was capable of enhancing TNF α production by macrophages initiated by other compounds. Dr. Chen's team believes that the effects of hemp oil enriched with CBD on immune cells may be used to improve cancer treatment, particularly in combination with other treatment modalities. In collaboration with Dr. Chen, ETST plans continued studies to determine the effects of hemp oil with CBD on inducing and enhancing anti-tumor immune responses. 

As always, ETST would like to thank Dr. Wei Chen and the College of Mathematics and Science at the University of Central Oklahoma for these recent reports, research, studies and tests on the effects of ETST High Grade CBD Rich Hemp Oil. Dr. Wei Chen, a veteran laser cancer treatment specialist who received his master's and Ph.D. degrees in theoretical high-energy physics from the University of Oregon, has done extensive work in the area of laser treatment of breast cancer and is working with a foreign drug company to advance and exploit the technology under development. Dr. Chen is a world renowned scientist, researcher and university professor whose laboratory is prominent in various areas including the application of CBD (Cannabidiol). Dr. Chen, who is also UCO's Assistant Dean of the College of Mathematics & Science, is a world-renown scientist and researcher, possessing a considerable decades-plus track record in laser breast cancer treatment research. Dr. Chen has published over 110 research articles to date and is a fellow of the leading not-for-profit interdisciplinary organization dedicated to advancing the science and application of light, the International Society for Optics and Photonics.

ABOUT ETST (www.earthsciencetech.com): ETST is a unique Biotechnology company focused on delivering cutting edge Nutraceuticals, Bioceuticals and Dietary Supplements designed for excellence in the areas of Health, Wellness, Sports and Alternative Medicine and to improving the quality of life for Consumers Worldwide. ETST is also dedicated to providing Natural Alternatives to prescription medications through the use of its cutting edge Nutritional and Dietary Supplements. This may include products such as its High Grade CBD (Cannabidiol) Hemp Oil, Vitamins, Minerals, Herbs, Botanicals, Personal Care Products, Homeopathies, Functional Foods and other products. These products may be in various formulations and delivery systems including (but not limited to) capsules, tablets, soft gels, chewables, liquids, creams, sprays, powders, and whole herbs. ETST is focused on researching and developing innovative Hemp extracts and to make them accessible Worldwide. ETST plans to be the premier supplier of the highest quality and purity of High Grade CBD (Cannabidiol) Hemp Oil. ETST's primary goal is to advance different High Quality Hemp extracts with a broad profile of Cannabinoids and additional natural molecules found in Industrial Hemp and to identify their distinct properties. The company is dedicated in offering its consumers the finest and purest quality All Natural-Organic CBD Rich Hemp oil while never compromising on quality. ETST High Grade CBD (Cannabidiol) Rich Hemp oil is classified as "food based" and therefore perfectly permissible in all 50 states and more than 40 countries. Cannabinoids (Cannabidiol/CBD) are natural constituents of the Hemp plant and CBD is derived from Hemp stalk and seed. Hemp oil is a well-known dietary supplement and the naturally occurring CBD possesses no psychoactive qualities and presents a continuing stream of overwhelming evidence of significant Wellness benefits. With no psychoactive ingredient, CBD is a ready-for-market Hemp-based Nutraceutical. The United States Food and Drug Administration (FDA) currently considers non-THC hemp based cannabinoids, including CBD, to be "food based" and therefore saleable. These new non-psychoactive CBD-rich hemp oil products that ETST has geared up to market and distribute are beyond reproach. CBD (cannabidiol), a naturally occurring constituent of the Industrial Hemp plant, promotes and supports the nutritional health of aging bodies in particular. Source: US Government Patent #6,630,507 "Cannabinoids as antioxidants and neuroprotectants." ETST does not grow, sell or distribute any substances that violate United States Law or the controlled substance act. ETST does sell and distribute hemp based products.

ABOUT DV BIOLOGICS, LLC (www.dvbiologics.com): DV Biologics is a global supplier of human biological tools to academic institutions and pharmaceutical companies engaging in cell and drug based discovery and development. Our mission is to provide biological tools needed to advance the innovation of technology that will ultimately be used to treat or prevent multiple human degenerative disorders and diseases. DV Biologics offers a diverse range of novel human biological tools and services that can be used to study various human pathological conditions in addition to an expanded product portfolio of unique cell types and tissue-derived products.

FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE: These statements and products have not been evaluated by the FDA and are not intended to diagnose, treat or cure any disease. Always check with your physician before starting a new dietary supplement program. 

FORWARD LOOKING DISCLAIMER: This release contains forward-looking statements that involve risks and uncertainties. Readers are referred to the Securities and Exchange Commission filings filed by the Company on EDGAR at http://www.sec.gov/edgar.shtml, specifically the most recent reports which identify important risk facts that could cause actual results to differ from those contained in the forward-looking statements. The Company undertakes no obligation to review or confirm analysts' expectations or estimates or to publicly release any revisions to any forward-looking statements. The information contained in this press release should not be construed as any indication of the Company's future stock price, its revenues or results of operations.

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