Given Imaging Announces Strong Presence at Upcoming Digestive Disease Week(R) 2012

YOQNEAM, ISRAEL--(Marketwire - May 18, 2012) - Given Imaging (NASDAQ: GIVN), a world leader in specialty GI products and pioneer of capsule endoscopy, today announced that a wide range of new studies will be presented at Digestive Disease Week® (DDW)® that confirm the value of its PillCam® SB, reflux and manometry products including Bravo, Digitrapper and Manoscan, and PillCam® COLON 2 in detecting and monitoring gastrointestinal diseases. Studies on the topics of pediatric Crohn's disease, upper gastrointestinal care, and new uses of PillCam SB will be presented, as well as studies on PillCam COLON 2. Given Imaging will be exhibiting at booth #2015 during DDW, taking place in San Diego from May 19-22, 2012.

"Given Imaging is proud of its role as a leader in developing innovative products for GI diagnostics," said Homi Shamir, president and CEO, Given Imaging. "Since 2001, when Given Imaging introduced capsule endoscopy to gastroenterologists, more than one and a half million PillCam capsules have been ingested by patients to help doctors improve the detection and monitoring of GI diseases. We thank the physicians and nurses who continue to advance clinical knowledge about diseases of the GI tract and to improve patient care."

Key studies to be presented at the meeting include:

Pediatric Crohn's Disease:

(Embargoed until May 19, 2012, 8 am PT)
Video Capsule Endoscopy Improves Clinical and Growth Outcomes in Pediatric IBD Patients (Sa1995)
Poster Presentation/Investigators: Steve B. Min, Minou Le-Carlson, Jennifer Gebbia, Kelly Haas, Shervin Rabizadeh, Neel K. Mann, Simon K. Lo, Gil Y. Melmed, Marla Dubinsky
Time: 8 am to 5 pm

(Embargoed until May 19, 2012, 8 am PT)
Mucosal Healing With the Specific Carbohydrate Diet in Pediatric Crohn's Disease: Preliminary Results of a Prospective Pilot Study (Sa1992)
Poster Presentation/Investigators: Stanley A. Cohen, Angela N. Stallworth, Bailey M. Koch, David H. Mason, Jeffrey Blumenthal, Benjamin D. Gold
Time: 8 am to 5 pm

New Uses of PillCam SB:

(Embargoed until May 19, 2012, 11:30 am PT)
The Twelve-Hour Battery Given Wireless PillCam SB2ex Improves Overall Cecal Intubation Rate and Increases the Positive Yield (153)
Topic Forum/Investigators: Neel K. Mann, Navin Paul, Simon K. Lo
Time: 11:30 am

(Embargoed until May 19, 2012, 2:30 PT)
Improved Diagnostic Yield with Early Video Capsule Endoscopy After Diagnosis of Obscure Gastrointestinal Bleeding (216)
Research Forum/Investigators: Dhavan A. Parikh, Mohit Mittal, Surinder K. Mann, Preethika S. Ekanayake
Time: 2:30 pm

(Embargoed until May 19, 2012, 8 am PT)
Capsule Endoscopy in Octogenarians: Analysis of a Large Prospectively Collected Database (Sa1742)
Poster Presentation/Investigators: Victoria Gomez, Mihir K. Patel, Mark E. Stark, Frank Lukens
Time: 8 am to 5 pm

(Embargoed until May 19, 2012, 8 am PT)
Improved Visualization of Small Bowel Lesions by Capsule Endoscopy Using Flexible Spectral Imaging Color Enhancement (FICE) System (Sa1592)
Poster Presentation/Investigators: Yasushi Sato, Masahiro Hirakawa, Hiroyuki Ohnuma, Kohichi Takada, Tsutomu Sato, Koji Miyanishi, Rishu Takimoto, Masayoshi Kobune, Junji Kato
Time: 8 am to 5 pm

PillCam COLON 2:

(Embargoed until May 19, 2012, 3:15 pm PT)
Capsule Colonoscopy with PillCam Colon 2 Is Feasible as an Out-Of-Clinic Procedure: (219)
Research forum/Investigators: Samuel N. Adler, Yishai Sompolinsky, Yoav C. Metzger, Cesare Hassan
Time: 3:15 pm

(Embargoed until May 21, 2012, 8 am PT)
PillCam Colon (C2) vs. Colonoscopy in the Assessment of Colon Mucosa in Patients with Ulcerative Colitis (Preliminary Data) (Mo1390)
Poster Presentation/Investigators: Mileidis E. San Juan-Acosta, Alba Belda-Cuesta, Angel Caunedo-Alvarez, Javier Romero-Vazquez, Blas J. Gomez-Rodriguez, Maria L. Morales, Federico Arguelles-Arias, Juan M Herrerias
Time: 8 am to 5 pm

Manometry:

(Embargoed until May 19, 8 am PT)
The High Resolution Manometric Profile of PPI Non-Responders (Sa1352)
Poster Presentation/Investigators: Yinglian Xiao, Joan Chen, Annemijn de Ruigh, Frédéric Nicodème, Mary Kwasny, Chang Lu, Lubomyr Boris, Gabriela I. Escobar, Peter J. Kahrilas, John E. Pandolfino
Time: 8 am to 5 pm

(Embargoed until May 22, 2012, 8 am PT)
How Accurate Is Computerized Analysis Versus an Expert Analysis for Evaluating Anorectal Function Using 3-D High Definition Anorectal Manometry (Tu1415)
Poster Presentation/Investigators: Enrique Coss-Adame, Jessica Valestin, Satish S. Rao
Time: 8 am to 5 pm

Additional Products:

(Embargoed until May 19, 8 am PT)
Slow Esophageal Propagation Velocity: a Finding in Patients With Dysphagia for Solids (Sa1196)
Poster Presentation/Investigators: Abhinav Sankineni, Lucy Salieb, Martha J. Harrison, Robert S. Fisher, Henry P. Parkman
Time: 8 am to 5 pm

(Embargoed until May 19, 8 am PT)
Impact of Esophageal Motor Disorders on Bolus Transit As Measured by Radionuclide Esophageal Transit Scintigraphy (Sa1199)
Poster Presentation/Investigators: Junichi Akiyama, Pankaj J. Pasricha, Linda Anh B. Nguyen
Time: 8 am to 5 pm

(Embargoed until May 19, 10:30 am PT)
Inter-Observer Agreement for Manometry Classification of Individual Swallows and Diagnoses Using High-Resolution Manometry (HRM) With Esophageal Pressure Topography (EPT): Results of Web-Based Studies With High Participation (1137a)
Topic Forum/Investigators: Mark R. Fox, John E. Pandolfino, Jafar Jafari, Dieter Menne, Ana T. Abreu, Auke Bogte, Alessandra Elvevi, Antonio Ruiz de Leon, Boudewijn F. Kessing, Lubomyr Boris, Jose M. Remes Troche, C. Prakash Gyawali, Candice L. Wilshire, Dorata Wasko-Czopnik, Francois Mion, Heiko Fruehauf, Frank Zerbib, Oliver Gellersen, Henriette Heinrich, Julio Perez de la Serna, Matthias M. Sauter, Gerrit J. Hemmink, Marcin Banasiuk, Miguel A. Valdovinos, Uscinowicz Miroslawa, Monika A. Kwiatek, Jeff Wright, Pim W. Weijenborg, Rami Sweis, Sabine Roman, Rukiye Vardar, Sudip K. Ghosh, Radu Tutuian, Wout O. Rohof, Albert J. Bredenoord
Time: 10:30 am

(Embargoed until May 19, 2012, 8 am PT)
Risk Stratification of Upper GI Bleeding With PillCam ESO Capsule (Sa1726)
Poster Presentation/Investigators: Sujievvan Chandran, Paul Urquhart, Adam Testro, Sim Ong, Edward Shelton, Richard La Nauze, Rhys Vaughan, William Kemp, Gregor J. Brown, Paul R. Froomes
Time: 8 am to 5 pm

(Embargoed until May 20, 8 am PT)
Extending BRAVO pH Monitoring Studies to Four Days: Patient Stratification Based on the Number of Positive Days (Su1100)
Poster Presentation/Investigators: Gabriela I. Escobar, Meghan Thompson, Meghan Barrett, Chang Lu, Lubomyr Boris, Peter J. Kahrilas, John E. Pandolfino
Time: 8 am to 5 pm

About Digestive Disease Week®
DDW is the largest international gathering of physicians, researchers and academics in the fields of gastroenterology, hepatology, endoscopy and gastrointestinal surgery. Jointly sponsored by the American Association for the Study of Liver Diseases, the American Gastroenterological Association (AGA) Institute, the American Society for Gastrointestinal Endoscopy and the Society for Surgery of the Alimentary Tract, DDW takes place May 19 - 22, 2012, at the San Diego Convention Center. The meeting showcases more than 5,000 abstracts and hundreds of lectures on the latest advances in GI research, medicine and technology. For more information, visit www.ddw.org.

About Given Imaging Ltd.
Since pioneering the field of capsule endoscopy in 2001, Given Imaging has become a world leader in GI medical devices, offering health care providers a range of innovative options for visualizing, diagnosing and monitoring the digestive system. The company offers a broad product portfolio including PillCam® video capsules for the small bowel, esophagus and colon, industry-leading ManoScan™ high resolution manometry and Bravo® pH and Digitrapper® pH and impedance products. Given Imaging is committed to delivering breakthrough innovations to the GI community and supporting its ongoing clinical needs. Given Imaging's headquarters are located in Yoqneam, Israel, with operating subsidiaries in the United States, Germany, France, Japan, Australia, Vietnam and Hong Kong. For more information, please visit www.givenimaging.com.

Forward-Looking Statements
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