SOURCE: International Society for Heart and Lung Transplantation

International Society for Heart and Lung Transplantation

April 18, 2015 02:00 ET

Heart and Lung Transplantation Research Makes Strides in Emerging Countries

NICE, FRANCE--(Marketwired - April 18, 2015) - This week at the International Society for Heart and Lung Transplantation's (ISHLT) 35thAnnual Meeting and Scientific Sessions in Nice, France, approximately 3,000 of the greatest minds in heart and lung transplantation gathered to listen and present research from around the globe. Presentations included that latest research from around the world which reinforced the progress emerging countries have made in heart and lung transplantation. Including studies that heart transplant patients show survival rates increasing in Saudi Arabia, new strategies being developed leading to increased lung transplant survival rates in Argentina and Uruguay.

"Data presented this week during the ISHLT meeting shows the potential for emerging countries and their increased success with heart and lung transplantations," said Andreas Zuckermann, MD, ISHLT 2015 Scientific Program Committee Chair. "Our organization is excited to see so much activity from the research community in theses countries, as it will only further our collegial efforts to make progress in heart and lung research."

Kazakhstan Sees Improvement in Three-Year Study

Research from the National Research Center for Cardiac Surgery in Astana, Kazakhstan, followed 139 patients from November 2011 to October 2014. Patients received a ventricular assist device (VAD), a device dedicated to support heart function and blood flow for patients with weakened hearts, as destination therapy and the results concluded survival rates increasing over time. The study finds the increase due to better patient selection, improved postoperative care, increased knowledge an team training, reliable devices, sufficient financial reimbursement and governmental support. Especially noteworthy was the survival rate in 2013 increased by 14-16% from 2012 in VAD patients.

National Heart Centre Singapore Study LVADs are Feasible in Multiracial Society

A study from 2009 to 2014 saw 50 patients receive implantation of an left ventricular assist device (LVAD) as a both bridge to transplant and destination therapy. Results show that in a multi-ethnic population of Singapore, LVADs are tolerated and long-term mortality and morbidity rates are comparable to other centres.

Current Status of Heart Transplantation and Mechanical Circulatory Support in Turkey

In a country of 75 million, a study lead by the Siyami Ersek Hospital in Istanbul, Turkey, estimates the incidence of heart failure to be around 2.4%. Since the countries first implantation of a VAD in 1998 over 400 devices have been implanted in patients. The two challenges the research suggests are critical factors in the treatment of advanced heart failure are organ donations and device reimbursements. The study concludes that the organ donation shortage is not related with religious beliefs.

King Faisal Specialist Hospital & Research Centre (KFSH&RC) Says its Ready to handle Heart Transplantations patient referrals from all Gulf countries.

Researchers executed a retrospective analysis of previously collected data from all heart transplantations in Saudi Arabia since 1989 through October 2014. During this time, 2014 patients underwent heart transplantation. Five and 10 year survival rates were 70 percent and 56 percent, respectively. The study notes survival data was significantly higher in new transplantations since 2006 due to greater experience of staff, immunosuppressive therapy, despite significantly older recipients and donors.

International Collaborations Results in Positive Impact in Lung Transplantation in Argentina and Uruguay

A study looked at post lung transplant outcomes after an international collaboration agreement was struck in 2003 that allows all lung transplant patients from Uruguay to receive the procedure at a single centre in Argentina at the University Hospital Favaloro Foundation in Buenos Aires. Researchers analyzed two group sets, patients who received a transplant between 1994 and 2010 and patients between 2011 and 2014. The latter group saw a lower in-hospital mortality rate (24 percent compared to 11 percent, respectively) and a higher two year survival rate (54 percent compared to 87 percent). The study concluded that a new lung allocation policy, established in December 2010, contributed to the success of group two in the study.

Additional research from emerging countries:

Significant Increase of Heart Transplantation Rates in Slovenia

Chile Establishes Two Lung Transplantation Centres

The International Society for Heart and Lung Transplantation (ISHLT) is a not-for-profit professional organization with more than 2,700 members from over 45 countries dedicated to improving the care of patients with advanced heart or lung disease through transplantation, mechanical support and innovative therapies via research, education and advocacy. For more information, visit www.ishlt.org.

International Society for Heart and Lung Transplantation

The International Society for Heart and Lung Transplantation (ISHLT) is a not-for-profit professional organization with more than 2,700 members from over 45 countries dedicated to improving the care of patients with advanced heart or lung disease through transplantation, mechanical support and innovative therapies via research, education and advocacy. For more information, visit www.ishlt.org.

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