SOURCE: IBC Life Sciences

March 20, 2007 17:26 ET

IBC's 3rd Annual Cell Line Engineering and Development Conference to Address Maximizing Expression Levels Through Total Process Optimization

WESTBOROUGH, MA -- (MARKET WIRE) -- March 20, 2007 -- IBC's 3rd annual conference on Cell Line Engineering and Development, to be held June 25-27 at the Hilton La Jolla Torrey Pines in La Jolla, CA, is designed for scientists, engineers and executives working on cell line selection and development programs. The conference includes presenters from both industry and academia and will detail the most recent technological advances and the results from key decisions made throughout the process. There will be over 150 upstream processing experts in attendance.

The Cell Line Development and Engineering conference will address details on the latest industry and academic research directed at cell line selection and development programs. Sessions to cover:

--  Proven strategies for choosing the right molecule to express
--  Transient transfection for discovery and clinical supplies
--  Smoothing the transition between antibody engineering and process
    development
--  New methods for analyzing and predicting cell line stability
--  Application of novel techniques for optimizing expression levels
--  Rational methods of developing cell culture media
--  Tools for rapid identification and production of high yielding cell
    lines
    
Three keynote addresses will be presented:
* The Cellular Response to Unfolded Protein in the Endoplasmic Reticulum,
  Randal J. Kaufman, Ph.D., University of Michigan Medical Center
* Toward Genomic Cell Culture Engineering
  Wei-Shou Hu, Ph.D., Professor, University of Minnesota
* BI HEX - Platform for Fast Track Generation of High Producer Cell Lines
  Leading to High-Titer Processes for Production of Therapeutic Proteins
  from Mammalian Cells
  Lore Florin, Ph.D., Senior Scientist, Cell Biology,
  Boehringer Ingelheim Pharma GmbH & Co.
A featured presentation on Transient Gene Expression in Mammalian Cells - Micrograms Synthesis for Research to Kg Manufacture of Recombinant Proteins for Clinical Applications: Current Reality and Future Directions will be given by Florian Maria Wurm, Ph.D., Professor of Biotechnology, Swiss Federal Institute of Technology Lausanne.

The technology workshop, ClonePix for Clone Selection: Lessons Learned from the Trenches, discusses automated high-throughput methods for selective cloning of mammalian cells for protein production.

ATTENTION CALENDAR EDITORS! For more information on attending Cell Line Development and Engineering at the Hilton La Jolla Torrey Pines in La Jolla, CA visit http://www.ibclifesciences.com/b4189.

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