ORTHOsoft Inc.

ORTHOsoft Inc.

March 22, 2006 08:45 ET

Leading Surgeons Present ORTHOsoft's New Knee and Hip Computerized Surgery System at AAOS, South Hall A Booth #4243

MONTREAL, QUEBEC--(CCNMatthews - March 22, 2006) - ORTHOsoft Inc. (TSX VENTURE:OSH), a computer-assisted surgery company that develops and markets software, instruments and computer systems that increase the accuracy of knee and hip surgery, announces that two leading orthopedic surgeons will present ORTHOsoft's new software and instruments used in innovative total knee and hip replacement procedures at the American Academy of Orthopaedic Surgeons (AAOS) conference in Chicago (March 22-26, 2006).

The presentations which take place at the ORTHOsoft booth (South Hall A booth #4243) at AAOS will be given by acclaimed surgeons, Dr. Aaron Hoffmann, from University of Utah Hospital in Salt Lake City (1:00 pm, March 22), and Dr. Lawrence Dorr, from Centinella Hospital in Los Angeles (1:00pm, March 23).

The milestone event for ORTHOsoft is that the simple and economic software can be used by surgeons who use implants from several different manufacturers. Many surgeons believe that the software is particularly well adapted to those who perform minimally invasive surgical techniques leading to faster recovery of the patients than conventional total knee and hip replacement techniques.

"ORTHOsoft's computer assisted surgery system not only ensures absolute position accuracy and enables minimally invasive surgery (MIS), it allows us to be better surgeons, and have better patient results" said Dr. Dorr. He added that, "This advanced system and total hip replacement technique using a 3 inch incision allows patients freer movement immediately after surgery and enables them to return home within one day using only a cane."

Orthopaedic Surgery Market

In North America and Europe, surgeons perform close to two million orthopaedic knee and hip implant surgeries annually. Many leading orthopaedic surgeons predict that computer assisted surgery will become a standard of care in implant surgery. The Company estimates its new universal knee and hip solutions will cover 80 % of the implants in use in the United States and European market.

To date, ORTHOsoft's computer assisted surgery systems have guided surgeons in more than 25,000 hip and knee surgeries in Europe and North America, and ORTHOsoft is well positioned to become a leader in the orthopaedic surgery market.

About ORTHOsoft

ORTHOsoft Inc. (TSX-V: OSH, www.orthosoft.ca), founded in 1995, develops and markets best-in-class medical software, instruments and computerized systems to assist orthopaedic surgeons to increase accuracy in hip, knee and spine implant surgery. FDA approved, ORTHOsoft's patented software solutions are developed by surgeons for surgeons, resulting in intuitive and easy-to-use navigation that tracks surgical flow and provides surgeons with real-time data that improves the surgical process and patient outcomes. To date, ORTHOsoft's software applications have navigated more than 25,000 surgical procedures in Europe and North America. For more information about ORTHOsoft, please visit www.orthosoft.ca.

Certain statements contained in this news release, other than statements of fact that are independently verifiable at the date hereof, may constitute forward-looking statements. Such statements, inherently involve numerous risks and uncertainties, known and unknown, many of which are beyond the control of ORTHOsoft, Inc. Such risks include, but are not limited to: the impact of general economic conditions, general conditions in the medical industry, and changes to the competitive environment in the jurisdictions in which ORTHOsoft does business, regulatory changes to the health care industry, and adequate protection of the proprietary interests of the Company. Consequently, actual future results may differ materially from the anticipated results expressed in the forward-looking statements. The reader should not place undue reliance on the forward-looking statements included in this press release. These statements speak only as of the date made, and ORTHOsoft is under no obligation and disavows any intention to update or revise such statements as a result of any event, circumstances, or otherwise.

Forward-looking statements contained in this press release involve known and unknown risks, uncertainties or other factors that may cause actual results, performance or achievements of the Company to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements.

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