SOURCE: Ludesi

October 17, 2007 10:54 ET

Ludesi Presents Results From Scientific Study on Discovery Potential in 2D Gel Image Analysis at the International HUPO 2007 Conference

Poster Details New Metrics for Measuring Accuracy of 2DGE Image Analysis Experiments

BOSTON, MA--(Marketwire - October 17, 2007) - Ludesi AB, provider of the industry-leading Image Analysis Service for 2-dimensional electrophoresis gels, presented results from an extensive study on how to optimize discovery potential in 2D gel image analysis at the International HUPO conference held in Seoul, South Korea last week.

The study is based on customer data from 30 different 2D gel image analyses projects comprising 474 gel images analyzed by market-leading software such as PDQuest, DeCyder, Progenesis, Progenesis with SameSpots, Image Master and Ludesi.

"The aim of this study is to find and define metrics that can be used to optimize discovery potential and minimize false discovery rate in 2D gel image analysis," says Ola Forsstrom-Olsson, founder and CEO of Ludesi. "Even though 2D gel image analysis software has been around for decades, there is still no really good way of measuring or estimating how reliable and complete an image analysis is. Our study results clearly indicate that it is possible to measure and predict discovery potential and false discovery rate in 2D gel image analysis."

The poster titled "How to Predict Discovery Potential and False Positives in 2-Dimensional Electrophoresis Image Analyses" can be viewed at:

About Ludesi 2D Gel Image Analysis Service

In two-dimensional gel electrophoresis (2DGE) experiments, the image analysis plays a crucial part in the overall reliability and accuracy of the results from an experiment. The Ludesi Image Analysis Service is designed for scientists and researchers at medical institutions and biopharmaceutical companies that want fast, high quality image analysis results without the cost of software or time required to manually produce analysis results. Ludesi is able to produce unbiased, consistent, reliable results compared to using conventional software, and at the same time, significantly reduce the false discovery rate among the results. Because it is a service, scientists and researchers do not have to purchase software, be trained, or spend valuable time performing the analysis.

About 2-Dimensional Gel Electrophoresis

Two-dimensional gel electrophoresis (2DGE) is a key technology in the growing field of proteomics, which involves the study of protein structure, expression and function within a cell. The study of the proteome is of vital importance because most diseases are discovered from biomarkers produced at the level of protein activity. Accurate detection and analysis of the characteristics, changes, and shapes of key proteins can speed up the identification of new drug targets that can be used to diagnose and treat diseases. In two-dimensional gel electrophoresis (2DGE) experiments, the image analysis plays a crucial part in the overall reliability and accuracy of the results from an experiment.

About Ludesi AB

Ludesi is a global provider of bioinformatics solutions to the life science industry. The company is serving some of the most prestigious research facilities in the world with image analysis of 2D electrophoresis gels on a per-sample basis. Ludesi's analysis is performed at the Ludesi Analysis Center with proprietary software technology and strict quality control to ensure accurate and reliable results. Further information can be found at

Ludesi is a Registered Trademark of Ludesi AB. All other trade names and trademarks are the property of their respective owners.

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