MBio Diagnostics Announces a Development Collaboration With Cincinnati Children's Hospital Medical Center

BOULDER, CO--(Marketwired - September 13, 2016) - MBio Diagnostics, Inc., a company leading a new era in rapid, on-the-spot clinical diagnostics and sample testing, today announced a product development collaboration with Cincinnati Children's Hospital Medical Center. Researchers at Cincinnati Children's, led by Hector Wong, MD, director, Division of Critical Care Medicine, have been investigating biomarker panels that provide prognostic and predictive patient stratification, particularly in the context of septic shock. MBio will collaborate with Dr. Wong to develop a multi-marker panel to risk stratify patients with septic shock in a clinically relevant time frame.

"I am particularly excited about the MBio technology because of its ability to deliver multiple results in near real-time with the ease-of-use required for implementation in critical care settings," said Dr. Wong. "The MBio Array System has the potential to be a unique and important new tool for immune system and host response monitoring." Cincinnati Children's is providing institutional funding through their Innovation Fund for this product development partnership. MBio Diagnostics will work with Dr. Wong to adapt the existing panel of tests to the MBio platform.

Prognostic and predictive patient stratification are fundamental elements of precision medicine, which seeks to target patient populations in which a drug or intervention is more likely to be effective. Prognostic enrichment strategies select patients with a greater likelihood of having a disease-related event. Predictive enrichment strategies select patients who are more likely to respond to an intervention or drug, based on a biological or physiologic mechanism. Enrichment strategies are particularly effective when selecting patients for treatment trials in highly heterogeneous syndromes, such as septic shock. By using prognostic and predictive strategies in trial design, therapies for critically ill patients can be optimized more quickly. Ultimately this approach will provide precision guidance to therapy in the clinic. In the context of critical care, these precision medicine techniques would ideally be carried out in real-time.

The MBio Array System utilizes MBio's proprietary LightDeck^® technology, which enables simple, multiplex testing in a compact system. This portable, easy-to-use multiplex reader can be placed into a wide variety of clinical situations, including directly placed in the intensive care unit (ICU). According to MBio CEO Chris Myatt, application partnerships are an important aspect of MBio's business strategy. "The biomarker panel developed by Dr. Wong and delivered in real time is the first step towards precision medicine at the point of care," said Dr. Myatt. "Adapting high-value content, such as derived from Dr. Wong's outstanding investigations of pediatric sepsis patients, provides unique solutions to very challenging healthcare problems."

About MBio Diagnostics

MBio Diagnostics is leading a new era in rapid, on-the-spot clinical diagnostics and sample testing. Our portable MBio Array System and disposable cartridges enable low-cost, rapid answers in 1 to 20 minutes. MBio aims to be the platform of choice for leading providers and users of clinical and analytical testing services in all market segments including: medical, veterinary, environmental, food, agricultural and military. www.mbiodx.com

About Cincinnati Children's

Cincinnati Children's, a non-profit, pediatric, academic medical center established in 1883, is internationally recognized for improving child health and transforming delivery of care through fully integrated, globally recognized research, education and innovation. It is one of the top three recipients of pediatric research grants from the National Institutes of Health, ranked third in the nation among all Honor Roll hospitals in U.S. News and World Report's Best Children's Hospitals, and a research and teaching affiliate of the University of Cincinnati's College of Medicine. Its patient population includes the eight-county primary service area covering parts of Ohio, Kentucky and Indiana. A destination for children with complex medical conditions, it also served patients from all 50 states and nearly 70 countries during the past year. Additional information can be found at www.cincinnatichildrens.org. Connect on the Cincinnati Children's blog, via Facebook and on Twitter.