Med BioGene Inc.
TSX VENTURE : MBI

Med BioGene Inc.

September 12, 2007 08:30 ET

Med BioGene Welcomes Renowned Expert to Lymphoma Collaboration

VANCOUVER, BRITISH COLUMBIA--(Marketwire - Sept. 12, 2007) - Med BioGene Inc. (TSX VENTURE:MBI), a life science company focused on the development and commercialization of genomic-based diagnostic and screening tests for cancer and cardiovascular disease, is pleased to welcome Sandeep S. Dave, M.D. of Duke University to its lymphoma collaboration. MBI and Duke entered into a research collaboration and option agreement in March 2007.

Dr. Dave came to Duke this summer as an Assistant Professor in the Institute for Genome Sciences and Policy and in the Department of Medicine's Division of Medical Oncology. Prior to joining Duke, Dr. Dave was a postdoctoral fellow at the laboratory of Louis Staudt at the National Cancer Institute. At the Staudt laboratory, Dr. Dave was involved in translational research aimed at using gene expression profiling to understand the role of differentially activated molecular pathways in non-Hodgkin lymphoma.

Dr. Dave has authored numerous articles in peer reviewed journals, including two as lead author in the New England Journal of Medicine, "Molecular Diagnosis of Burkitt's lymphoma" and "Prediction of Survival in Follicular Lymphoma based on Molecular Features of Tumor-Infiltrating Immune Cells".

Dr. Dave attended graduate school, medical school and completed his residency in internal medicine at Northwestern University. He completed a fellowship in hematology and medical oncology at the National Institutes of Health.

"I am very excited to work with Med BioGene and to expand upon the work that I undertook at the National Cancer Institute. Gene expression profiling has demonstrated that lymphoma types that were previously regarded as homogenous can harbor subgroups that are dramatically different in their biology and responses to therapy. Such studies could form the basis for risk stratification and tailored therapies that are most likely to benefit molecularly defined subgroups of patients," noted Dr. Dave.

"Dr. Dave is a world renowned expert in the research of gene expression profiling of lymphoma and we are very pleased to be working with him and Dr. David A. Rizzieri, Associate Professor of Medicine and Director, Hematologic Malignancy Program at Duke University. Our collaboration with Duke is central to the development of our first genomic-based clinical laboratory diagnostic test for lymphoma, LymphExpress Dx™," said Erinn B. Broshko, Chief Executive Officer of MBI.

About Med BioGene

MBI is a life science company focused on the development and commercialization of genomic-based clinical laboratory diagnostic and screening tests for cancer and cardiovascular disease. MBI develops these tests by identifying the genes, known as "biomarkers", which indicate the presence of disease. The development of these tests is the first step towards personalized medicine and will replace the conventional "one drug fits all" approach to disease management.

Expected benefits include:

- more accurate, quicker and less invasive diagnosis;

- tailoring of treatment decisions to the needs of each patient by outlining a patient's genetic profile, thus making treatment more effective and reducing healthcare costs by minimizing the treatment of non-responders; and

- prioritizing of genomic biomarkers for use as potential therapeutic targets and to validate the effectiveness of specific therapeutics.

MBI is currently developing tests for lymphoma, leukemia and cardiovascular disease through the following products: LymphExpress Dx™, LeukExpress Dx™ and CardioExpress Dx™.

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