SOURCE: Accelrys


October 07, 2010 09:00 ET

New Drawing Software From Accelrys Bridges Chemistry and Biology

Accelrys Draw 4.0 Improves Representation of Chemically Modified Biological Sequences

SAN DIEGO, CA--(Marketwire - October 7, 2010) -  Accelrys, Inc. (NASDAQ: ACCL), the leading scientific informatics software and services company, today announced the release of Accelrys Draw 4.0 (previously Symyx Draw). Accelrys Draw enables scientists to draw, edit, compare, and explore complex biological sequences along with chemical structures and reactions -- improving intellectual property (IP) management and operational efficiency in today's increasingly interrelated chemical and biological research environment.

"Supporting the rapid growth of biologics in R&D pipelines, Accelrys Draw 4.0 enables scientists to draw chemically significant, modified peptides and bioconjugates," said Dr. Trevor Heritage, executive vice president, software products, Accelrys. "For example, scientists using Accelrys Draw can design biological entities such as siRNAs that contain bases, peptides, and novel linkers. These components enable the biologics to enter cells by escaping the normal processes that destroy unnatural RNA strands."

"The award-winning Accelrys Biologics Registration system will benefit from the enhanced capabilities of Accelrys Draw and Accelrys Direct, enabling the rigorous capture of biological sequences," said Dr. Frank Brown, senior vice president and chief science officer, Accelrys. "Customers now have a unified registration system for molecules of any size, biologics and formulations -- and this unified system greatly reduces the complexity of end-to-end data aggregation."

In combination with the Accelrys Direct data cartridge and supporting the Accelrys Biological Registration system, Accelrys Draw 4.0 offers scientists unique capabilities for managing complex biological entities including the ability to

  • Import sequence files from the Universal Protein (UniProt) Resource for viewing, editing, and interpretation
  • Mutate and modify residues using standard and custom libraries of modifications
  • Add custom residues and linkers, PEGylation, and natural and unnatural lactone and lactam formations
  • Protect IP by registering modified sequences in a corporate database. Duplicate checking, exact matching, molecular weight calculation, and substructure searching are all available with these structures.

Accelrys Draw 4.0 and the recently released Accelrys Direct 7.0 data cartridge (previously Symyx Direct) both support a new, compact, and scalable hybrid representation that combines the best features of bioinformatics and cheminformatics notations. This hybrid representation improves multidisciplinary collaborative research by enabling scientists to register and retrieve molecules, reactions, and biomolecular sequences including peptides, oligonucleotides, and oligosaccharides. Scientists can also search for and view chemical modifications in sequences and develop structure-activity correlations in sequences.

For more information, read the blog posting, "Representing Biologics: Where Chemiformatics and Bioinformatics Collide." For a hands-on trial, request a 30-day FREE evaluation of the new-generation Accelrys Draw chemical and biological drawing tool.

About Accelrys, Inc.
Headquartered in San Diego, California, Accelrys develops scientific informatics software and solutions for the life sciences, energy, chemicals, aerospace, and consumer products industries. Customers include many Fortune 500 companies and other commercial entities, as well as academic and government entities. Accelrys has a vast portfolio of computer-aided design modeling and simulation offerings which assist customers in conducting scientific experiments 'in silico' in order to reduce the duration and cost of discovering and developing new drugs and materials. Its scientific informatics platform underlies the company's computer-aided design modeling and simulation offerings. The Accelrys platform can be used with both Accelrys and competitive products, as well as with customers' proprietary predictive science products. Its flexibility, ease-of-use and advanced chemical, text and image analysis and reporting capabilities enable customers to mine, aggregate, analyze and report scientific data from disparate sources, thereby better utilizing scientific data within their organizations. In July 2010, Accelrys and Symyx Technologies, Inc. merged, combining the market-leading Symyx electronic laboratory notebook, decision support software, and chemical informatics and sourcing databases with the Accelrys portfolio of scientific informatics solutions. For more information about Accelrys solutions, visit