SOURCE: Oryzon Genomics

Oryzon

May 18, 2016 08:00 ET

ORYZON to Extend Its R&D Collaborationon ORY-1001 Until March 2017

BARCELONA, SPAIN and CAMBRIDGE, MA--(Marketwired - May 18, 2016) -  Oryzon Genomics (ISIN Code: ES0167733015), a clinical-stage biopharmaceutical company leveraging epigenetics to develop therapies in oncology and neurodegenerative diseases, announced today that the 2-year R&D collaboration with Roche concerning ORY-1001, licensed to Roche in 2014, has been extended until March 2017.

ORY-1001 (RG6016) is a highly potent and selective inhibitor of LSD1 currently in Phase I/IIA in acute leukemia patients. The license agreement by which the development and commercial rights to ORY-1001 were granted to Roche, included a 2-year collaborative research program between Oryzon and Roche to further explore the potential of ORY-1001 in oncology and haematology. The program has delivered additional insight into the drug's mechanism of action, provided support for its use in indications beyond acute leukemia and has expanded the toolbox for future and current clinical trials. Oryzon will continue to support the development of ORY-1001 through an extension of the collaborative research program that will run until March 2017 with the main goal to finalize the transfer of the newly generated technology and knowledge.

Carlos Buesa, Oryzon's CEO, has declared: "This collaboration between Roche and Oryzon has been highly satisfactory and the success of the collaboration is reflected in four newly filed patent applications. We have been impressed by the experience of our partner and are convinced the results generated will strengthen the further clinical development of ORY-1001."

About Oryzon

Founded in 2000 in Barcelona, Spain, Oryzon (ISIN Code: ES0167733015) is a clinical stage biopharmaceutical company considered as the European champion in Epigenetics. The company has one of the strongest portfolios in the field and a clinical asset already partnered with Roche. Oryzon's LSD1 program is currently covered by 20 patent families and has rendered two compounds in clinical trials. In addition, Oryzon has ongoing programs for developing inhibitors against other epigenetic targets. The company has a strong technological platform for biomarker identification and performs biomarker and target validation for a variety of malignant and neurodegenerative diseases. Oryzon's strategy is to develop first in class compounds against novel epigenetic targets through Phase II clinical trials, at which point it is decided on a case-by-case basis to either keep the development in-house or to partner or out-license the compound for late stage development and commercialization. The company has offices in Barcelona and Cambridge, Massachusetts. For more information, visit www.oryzon.com.

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