SOURCE: Patient-Centered Outcomes Research Institute

Patient-Centered Outcomes Research Institute

August 17, 2016 13:03 ET

PCORI Makes More Than $350 Million in Research Support Available Through Latest Funding Announcements

Opportunities Include Funding for Studies of Pelvic Prolapse Treatment, Pneumonia, Opioid Prescribing, Palliative Care, and Sickle Cell Disease

WASHINGTON, DC--(Marketwired - August 17, 2016) - The Patient-Centered Outcomes Research Institute (PCORI) has issued 10 new calls for research proposals, offering up to $351 million in funding for patient-centered comparative clinical effectiveness research (CER) through these announcements. The goal is to fill gaps in knowledge about which healthcare options work most effectively for which patients.

Research teams that wish to apply for any of these funding opportunities first must submit a Letter of Intent (LOI) by 5 p.m. ET Wednesday, Sept. 14.

One of the new PCORI Funding Announcements (PFAs) will make a total of up to $30 million available for up to six studies comparing ways to prevent unsafe prescribing of opioids to treat people with acute or chronic pain.

Another PFA offers up to $48 million for studies to improve palliative care planning for patients with advanced illnesses, as well as research comparing different palliative care delivery models in community settings.

A third offers up to $25 million for up to three studies comparing ways to manage the transition of people with sickle cell disease from pediatric to adult care.

PCORI also issued its latest PFA through its Pragmatic Clinical Studies Initiative, including special calls for proposals focused on comparing transvaginal mesh and other treatments for pelvic organ prolapse in women and alternative antibiotic regimens in treating adults with community-acquired pneumonia. Up to $40 million is earmarked for studies on each of these special emphasis topics. This is in addition to the up to $90 million available through this PFA for studies of dozens of other patient-centered research questions identified through PCORI's topic prioritization process and by other key groups.

Five additional funding announcements offer a total of up to $76 million in funds for researchers' best ideas for patient-centered CER projects under PCORI's National Priorities for Research.

PCORI will review LOIs for responsiveness and fit with program goals. Those invited to submit full applications will have until Monday, Dec. 19, to do so. Information and other key dates related to all of PCORI's funding opportunities can be found in the Funding Opportunities page on PCORI's website.


The Patient-Centered Outcomes Research Institute (PCORI) is an independent, non-profit organization authorized by Congress in 2010. Its mission is to fund research that will provide patients, their caregivers and clinicians with the evidence-based information needed to make better-informed healthcare decisions. PCORI is committed to continuously seeking input from a broad range of stakeholders to guide its work.

Contact Information