Protherics PLC announces Blocklisting Interim Review


Cheshire, UK -- (MARKET WIRE) -- February 9, 2007 --

                                 Protherics PLC



                  6 monthly Block Listing Return in respect of

                      6% unsecured convertible loan notes





London, UK; Brentwood, TN, US: 9 February 2007 - Protherics PLC ("Protherics" or
the "Company"), the international biopharmaceutical company focused on critical
care and cancer, announces that the following 6 monthly block listing return in
respect of the Company's 6% unsecured convertible loan notes has been lodged
with the FSA today, in accordance with Listing Rule 3.5.6.




Name of applicant:                                         Protherics PLC
Name of scheme:                                            Block Listing in respect of 6% Unsecured Convertible Loan
                                                           Notes
Period of return:                           From:          8 August 2006          To:        8 February 2007
Balance under scheme from previous return:                 9,617,236 Ordinary Shares (Loan Notes to the value of
                                                           £2,404,309.00)
The amount by which the block scheme has been increased,   68,200 Ordinary Shares (Loan Notes to the value of
if the scheme has been increased since the date of the     £17,050.00)
last return:
Number of securities issued/allotted under scheme during   768,040 Ordinary Shares (Loan Notes to the value of
period:                                                    £192,010.00)
Balance under scheme not yet issued/allotted at end of     8,917,396 Ordinary Shares (Loan Notes to the value of
period                                                     £2,229,349.00)
Number and class of securities originally listed and the   17,092,476 Ordinary Shares (Loan Notes to the value of
date of admission                                          £4,273,119.00) admitted on 8 February 2005
Total number of securities in issue at the end of the      339,086,994 Ordinary Shares
period



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For further information please contact:


Protherics
Nick Staples, Director of Corporate Affairs                                     +44 (0) 7919  480510
Julie Vickers, Company Secretary                                                +44 (0)1928 518000

Financial Dynamics - press enquiries
London: Ben Atwell, Anna Keeble                                                 +44 (0) 20 7831 3113
New York: John Capodanno, Jonathan Birt                                         +1 212 850 5600



Or visit  www.protherics.com




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