SOURCE: Protherics PLC

February 09, 2007 12:46 ET

Protherics PLC announces Blocklisting Interim Review

Cheshire, UK -- (MARKET WIRE) -- February 9, 2007 --

                                 Protherics PLC

                  6 monthly Block Listing Return in respect of

                      6% unsecured convertible loan notes

London, UK; Brentwood, TN, US: 9 February 2007 - Protherics PLC ("Protherics" or
the "Company"), the international biopharmaceutical company focused on critical
care and cancer, announces that the following 6 monthly block listing return in
respect of the Company's 6% unsecured convertible loan notes has been lodged
with the FSA today, in accordance with Listing Rule 3.5.6.

Name of applicant:                                         Protherics PLC
Name of scheme:                                            Block Listing in respect of 6% Unsecured Convertible Loan
Period of return:                           From:          8 August 2006          To:        8 February 2007
Balance under scheme from previous return:                 9,617,236 Ordinary Shares (Loan Notes to the value of
The amount by which the block scheme has been increased,   68,200 Ordinary Shares (Loan Notes to the value of
if the scheme has been increased since the date of the     £17,050.00)
last return:
Number of securities issued/allotted under scheme during   768,040 Ordinary Shares (Loan Notes to the value of
period:                                                    £192,010.00)
Balance under scheme not yet issued/allotted at end of     8,917,396 Ordinary Shares (Loan Notes to the value of
period                                                     £2,229,349.00)
Number and class of securities originally listed and the   17,092,476 Ordinary Shares (Loan Notes to the value of
date of admission                                          £4,273,119.00) admitted on 8 February 2005
Total number of securities in issue at the end of the      339,086,994 Ordinary Shares

                                   |  Ends  |

For further information please contact:

Nick Staples, Director of Corporate Affairs                                     +44 (0) 7919  480510
Julie Vickers, Company Secretary                                                +44 (0)1928 518000

Financial Dynamics - press enquiries
London: Ben Atwell, Anna Keeble                                                 +44 (0) 20 7831 3113
New York: John Capodanno, Jonathan Birt                                         +1 212 850 5600

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