Cheshire, UK -- (MARKET WIRE) -- January 4, 2007 --
PROTHERICS PLC NOTIFICATION OF INTERESTS OF DIRECTORS London, UK; Brentwood, TN, US; 4 January 2007: Protherics PLC ("Protherics" or the "Company"), the international biopharmaceutical company focused on critical care and cancer, announces that following completion of the Cash Placing, the Placing and Open Offer, the Glenveigh Licence and the MacroMed Acquisition and as a result of the Directors taking up all of their entitlements under the Placing and Open Offer at a price of 65 pence per share, the following directors' holdings in Ordinary Shares have changed as set out below: Number of Ordinary Shares Number of Ordinary Shares Percentage of issued taken up under the Open following the Open Offer share capital Offer S M Wallis 62,965 566,689 0.17 A J Heath 43,312 389,810 0.11 B M Riley 3,752 33,771 0.01 J C Christie 3,542 31,885 0.01 J R Brown 2,500 22,500 0.01 Protherics current issued Ordinary Share capital is 338,976,174 Terms used in this announcement shall have the same meaning as those used in the Company's prospectus dated 7 December 2006. ENDS For further information contact: Protherics PLC Barry Riley, CFO +44 (0) 1928 518 000 Julie Vickers, Company Secretary +44 (0) 1928 518 010 This information is provided by RNS The company news service from the London Stock Exchange