Protherics PLC
Notification of Major Interest in Shares
London, UK; Brentwood, TN, US; 8 August 2008 - Protherics PLC
("Protherics" or the "Company"), the international biopharmaceutical
company focused on critical care and cancer, announces that the
following notification of interest in the ordinary share capital of the
Company was received today from Aviva plc.
1. Reason for the notification (please tick the appropriate box
or boxes)
An acquisition voting rights X
An acquisition or disposal of financial instruments which may result
in the acquisition of shares already issued to which voting rights
are attached
An event changing the breakdown of voting rights
Other (please specify): CHANGE TO THE TOTAL NUMBER OF VOTING RIGHTS
IN ISSUE
2. Full name of person(s) subject to the Aviva plc & its
notification obligation: subsidiaries
3. Full name of shareholder(s) (if different from Registered Holder:
2.):
BNY Norwich Union
Nominees Limited
6,741,190*
Chase GA Group
Nominees Limited
17,297,355*
Chase Nominees
Limited
979,009*
CUIM Nominee Limited
5,150,906*
Vidacos Nominees
Limited
70,303*
BNP Paribas - London
636,429
Chase Nominees
Limited
3,518,325
State Street
Nominees Limited
9,577,375
Vidacos Nominees
Limited
2,180,596 *denotes direct
interest
4. Date of the transaction (and date on which the 6 August 2008
threshold is crossed or reached if different):
5. Date on which issuer notified: 8 August 2008
6. Threshold(s) that is/are crossed or reached: 12% to 13% Change
at Combined Interest
level
7. Notified details:
A: Voting rights attached to shares
Class/type Situation previous to Resulting situation after the trigger
ing
of shares the Triggering transaction
transaction
if possible
using the Number of Number of Number of Number of voting % of
voting
ISIN CODE Shares Voting shares rights righ
ts
Rights
Direct Direct Indirect Dire
ct Indirect
Ordinary
Shares
40,890,879 40,890,879 30,238,763 30,238,763 15,912,725 8.88
% 4.68%
GB0007029209
B: Financial Instruments
Resulting situation after the triggering transaction
Type of Expiration Exercise/ Number of voting rights that % of
financial date Conversion may be acquired if the voting
instrument Period/ instrument is exercised/ rights
Date converted.
N/A
Total (A+B)
Number of voting rights % of voting rights
46,151,488 13.56%
8. Chain of controlled undertakings through which the voting rights and
/or the financial instruments are effectively held, if applicable :
See Section 3
Proxy Voting:
9. Name of the proxy holder: See
Section 3
10. Number of voting rights proxy holder will cease to
hold:
11. Date on which proxy holder will cease to hold voting
rights:
12. Additional Figures are based on a total number of voting
information: rights of 340,417,123
/ Ends /
For further information please contact:
Protherics
Nick Staples, Director of Corporate Affairs +44 (0) 7919 480510
Julie Vickers, Company Secretary +44 (0)1928 518010
Financial Dynamics - press enquiries
London: Ben Atwell, Lara Mott +44 (0) 20 7831 3113
New York: John Capodanno +1 212 850 5600
Or visit www.protherics.com
This information is provided by RNS
The company news service from the London Stock Exchange
END
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