Protherics PLC Notification of Major Interests in Shares London, UK; Brentwood, TN, US: 23 November 2007 - Protherics PLC ("Protherics" or the "Company"), the international biopharmaceutical company focused on critical care and cancer, announces that on 22 November 2007, in accordance with the Transparency Obligations Directive, a notification of interest in the ordinary share capital of the Company was received from HBOS plc. Details of the interest notified are as follows: 1. Reason for the notification (please tick the appropriate box or boxes) A disposal of voting rights X An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Other (please specify): 2. Full name of person(s) subject to the HBOS plc notification obligation: 3. Full name of shareholder(s) (if different See Section 8 from 2.): 4. Date of the transaction (and date on which 21 November 2007 the threshold is crossed or reached if different): 5. Date on which issuer notified: 22 November 2007 6. Threshold(s) that is/are crossed or reached: Decrease to below 6% Direct and Indirect 7. Notified details: A: Voting rights attached to shares Class/type of Situation previous to the Resulting situation after the triggering transaction shares Triggering transaction if possible Number of Number of Number of Number of voting rights % of voting rights using the ISIN Shares Voting Rights shares CODE Direct Direct Indirect Direct Indirect Ord 2p Shares 20,918,307 20,918,307 1,308,983 1,308,983 18,936,943 0.386% 5.580% ISIN GB000702920 B: Financial Instruments Resulting situation after the triggering transaction Type of financial Expiration date Exercise/ Conversion Number of voting rights % of voting rights instrument Period/ Date that may be acquired if the instrument is exercised/ converted. N/A Total (A+B) Number of voting rights % of voting rights 20,245,926 5.966% 8. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: Insight Investment Management (Global) Limited* ('IIMGL') - (Indirect) - 20,222,375 (5.959%) IIMGL manages holdings on behalf of other HBOS Group companies, and other third parties external to the HBOS Group, under various discretionary management agreements. (* - wholly owned subsidiaries of HBOS plc). Proxy Voting: 9. Name of the proxy holder: N/A 10. Number of voting rights proxy holder will cease to hold: N/A 11. Date on which proxy holder will cease to hold voting rights: N/A 12. Additional information: Notification using the total voting rights figure of 339,346,822 | Ends | For further information please contact: Protherics Nick Staples, Director of Corporate Affairs +44 (0) 7919 480510 Julie Vickers, Company Secretary +44 (0)1928 518010 Financial Dynamics - press enquiries London: Ben Atwell, Lara Mott +44 (0) 20 7831 3113 New York: John Capodanno, Jonathan Birt +1 212 850 5600 Or visit www.protherics.com This information is provided by RNS The company news service from the London Stock Exchange
Protherics PLC announces Major Interest in Shares
| Source: Protherics PLC
Cheshire, UK--(Marketwire - November 23, 2007) -