Protherics PLC announces Voting Rights


Cheshire, UK -- (MARKET WIRE) -- February 28, 2007 --

                                 Protherics PLC

                     Total Voting Rights and Share Capital


London, UK; Brentwood, TN; 28 February 2007 - In conformity with the
Transparency Directive, Protherics PLC ("Protherics"), the international
biopharmaceutical company focused on critical care and cancer, notifies the
market of the following:

Protherics' issued share capital consists of 339,108,619 ordinary shares with a
nominal value of 2 pence each, with voting rights. Protherics does not hold any
ordinary shares in Treasury.

Therefore, the total number of voting rights in Protherics is 339,108,619.

The above figure of 339,108,619 shares may be used by shareholders as the
denominator for the calculations by which they will determine if they are
required to notify their interest in, or a change to their interest in,
Protherics under the Financial Services Authority's Disclosure and Transparency
Rules.

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For further information please contact:


Protherics
Nick Staples, Director of Corporate Affairs                 +44 (0) 7919  480510
Julie Vickers, Company Secretary                            +44 (0)1928 518010

Financial Dynamics - press enquiries
London: Ben Atwell, David Yates                             +44 (0) 20 7831 3113
New York: John Capodanno, Jonathan Birt                     +1 212 850 5600

Or visit  www.protherics.com


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