SOURCE: Protherics PLC

October 09, 2008 13:39 ET

Protherics PLC - Unapproved Share Option Scheme

Cheshire, UK--(Marketwire - October 9, 2008) -

                            Protherics PLC

                   6 monthly Block Listing Return

                   Unapproved Share Option Scheme

London, UK; Brentwood, TN; 9 October 2008 - Protherics PLC
("Protherics" or the "Company"), the international biopharmaceutical
company focused on critical care and cancer, in accordance with Listing
Rule 3.5.6, notifies the following details in respect of the block
listing for its Unapproved Share Option Scheme:

Name of applicant:                         Protherics PLC

Name of scheme:                            Protherics PLC Unapproved
                                           Share Option Scheme

Period of return:                From:     9 April   To: 8 October 2008

Balance of unallotted securities under     3,126,947scheme at beginning of period:

The amount by which the block scheme has   Nil
been increased during the period:

Number of securities issued/allotted under 50,000
scheme during period:

Balance under scheme not yet issued/       3,076,947
allotted at end of period

                                  / Ends /

For further information please contact:

Nick Staples, Director of Corporate Affairs      +44 (0) 7919 480510  
Julie Vickers, Company Secretary                 +44 (0)1928 518010

Financial Dynamics - press enquiries
London: Ben Atwell, Lara Mott                    +44 (0) 20 7831 3113 
New York: John Capodanno                         +1 212 850 5600

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