canadian marfan association

canadian marfan association

November 09, 2007 11:29 ET

Research Trial Represents Hope For Canadians With Marfan Syndrome

Attention: Health/Medical Editor, Lifestyle Editor MISSISSAUGA, ONTARIO--(Marketwire - Nov. 9, 2007) - A clinical trial currently being conducted in Canada, the U.S. and Belgium represents great hope for the 1 in 5000 Canadians living with Marfan Syndrome.

Marfan Syndrome is largely unknown and potentially fatal if undetected and untreated. This genetic disorder of the body's connective tissue can affect the skeletal system, eyes, lungs, blood vessels and most critically the aorta. People who have Marfan Syndrome have a high risk of developing an aortic aneurysm, which can lead to the rupture of the aorta, causing sudden death.

This important study, long awaited by the Marfan community, will compare the drugs losartan, a commonly prescribed blood pressure medication and atenolol, a beta-blocker currently used by Marfan patients. In April 2006 losartan was found to prevent many if not most of the features of Marfan Syndrome in a mouse model. The trial hopes to confirm if these positive effects will also occur in people.

As of August, 109 children and adults with Marfan Syndrome have entered the trial. We are extremely excited and optimistic about this study as the drug losartan represents the potential for a better treatment and quality of life for those living with Marfan Syndrome.

November 11-17, 2007 is National Marfan Awareness Week. This week gives us an opportunity to teach Canadians about this potentially life threatening disorder. National Marfan Awareness Week brings together Marfan patients, their families and friends to raise awareness in their local communities across Canada.

The Canadian Marfan Association is a non-profit charity dedicated to assisting Marfan patients and their families through programs of research, education and support.

For more information about Marfan Syndrome please visit our web site at

Please help us spread much needed awareness of Marfan Syndrome.

Contact Information

  • Eva Theofilopoulos, Executive Manager, Canadian Marfan Association
    Primary Phone: 905-826-3223
    Toll-Free: 866-722-1722