SOURCE: Seegene


April 29, 2009 08:49 ET

Seegene Introduces Diagnostic Test for Diarrhea

Seeplex® Diarrhea ACE Detection Tests for 14 Diarrhea Causing Pathogens

ROCKVILLE, MD--(Marketwire - April 29, 2009) - Seegene today introduced the Seeplex® Diarrhea ACE Detection test that provides a novel and fast-acting multiplex PCR diagnostic technique to simultaneously verify a complex range of pathogens that cause diarrhea. Based on the company's proprietary DPO (Dual Priming Oligo) technology, the Seeplex Diarrhea ACE Detection tests for ten bacteria (Salmonella spp., Shigella spp., Campylobacter spp., Vibrio spp., C. difficile Toxin B, C. perfringens, Y. enterocolitica, Aeromonas spp., E.coli0157:H7, Verocytotoxin-producing E.coli) and four viruses (Rotavirus, Norovirus, Enteric adenovirus, Astrovirus) that cause diarrhea.

By accurately detecting and differentiating diarrhea causing viruses from bacteria, the Seeplex Diarrhea ACE Detection test will help healthcare practitioners apply the correct course of treatment for patients at the earliest possible stage.

Caused by viruses and bacteria, fast and accurate diagnosis is crucial for the proper treatment of this highly contagious and common disease. The World Health Organization (WHO) estimates that about three million people die every year worldwide from diarrhea and its associated complications. Approximately 1.9 million of these fatalities are children under the age of five.

"70-80% of infectious diarrhea is caused by viruses, especially Norovirus and Rotavirus, which are also responsible for most of the food borne diarrhea outbreaks. Until now there have been no diagnostic methods capable of detecting these multiple and varied viruses accurately," said Dr. Jong-Yoon Chun, Founder and CEO of Seegene.

Another 10-20% of diarrhea cases result from bacterial infection. To avoid unnecessary treatment with general antibiotics that promote drug resistant bacteria, it is important to accurately differentiate viruses from bacteria, as well as identify pathogens at the early stage of infection.

Dr. Chun continued, "In the case of bacterial diarrhea, traditional diagnostic methods are microscopy, ELISA and stool culture, but these methods have notable limitations in terms of sensitivity, specificity, ease of use and speed. Taking only six hours to detect either bacterial or viral infection, Seeplex Diarrhea ACE Detection is an accurate, rapid and cost-effective diarrhea diagnostic tool that offers a new way for diagnosing diarrhea."

Seeplex Diarrhea ACE Detection is for research use only.

About Seeplex® System: Frontier of Multi-pathogen Detection

Seeplex® is a breakthrough multiplexing PCR technology that enables a new standard in simultaneous multi-pathogen detection. Seeplex works in combination with automatic detection systems such as Capillary Electrophoresis and delivers a benchmark in testing accuracy, efficiency and cost-effectiveness.

About Seegene

Seegene, Inc. is a biotechnology company specialized in molecular diagnostics and research applications. It holds a novel detection platform named "Seeplex," which sets a standard in high-throughput and simultaneous multi-pathogen detection called "multiplexing." Seeplex technology accurately detects multi-pathogens with high-throughput speed, ultimately providing the most economical basis for saving time, labor and cost. Seegene develops, manufactures and markets innovative molecular diagnostic products and services to a worldwide community. Its mission is to maintain leadership in molecular diagnostics for infectious diseases, genetics, pharmacogenetics, and oncology, and chromosomal analyses using innovative proprietary technologies. For more information please visit or call +301-762-9066.

Contact Information

  • Contacts:
    Hyunsoo Kim, Ph.D.
    Seegene Inc.
    Email Contact
    Constantine Theodoropulos
    Base Pair Communications