NOTIFICATION OF MAJOR INTERESTS IN SHARES
1. Name of company
Smith & Nephew plc
2. Name of shareholder having a major interest
Capital Research and Management Company
3. Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is
a holding of that person's spouse or children under the age of 18
Non-beneficial
4. Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them
Various
5. Number of shares / amount of stock acquired
4,892,054
6. Percentage of issued class
0.55%
7. Number of shares / amount of stock disposed
8. Percentage of issued class
9. Class of security
Ordinary shares of US 20 cents
10. Date of transaction
08.10.2008
11. Date company informed
09.10.2008
12. Total holding following this notification
46,119,030
13. Total percentage holding of issued class following this
notification
5.2255%
14. Any additional information
15. Name of contact and telephone number for queries
Gemma Parsons - Assistant Company Secretary
020 7960 2228
16. Name and signature of authorised company official responsible for
making this notification
Gemma Parsons - Assistant Company Secretary
Date of notification
10.10.2008
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