Smith & Nephew - Holding(s) in Company 2


London, UK--(Marketwire - December 17, 2008) -


NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Name of company


Smith & Nephew plc 


2. Name of shareholder having a major interest


Prudential plc


3. Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is
a holding of that person's spouse or children under the age of 18


Non-beneficial


4. Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them


Prudential Plc

........................



5. Number of shares / amount of stock acquired


300,000


6. Percentage of issued class


less than0.1%



7. Number of shares / amount of stock disposed



8. Percentage of issued class




9. Class of security


Ordinary shares of US 20 cents


10. Date of transaction


15.12.2008


11. Date company informed


16.12.2008


12. Total holding following this notification


26,945,366


13. Total percentage holding of issued class following this
notification


3.05%


14. Any additional information



15. Name of contact and telephone number for queries


Gemma Parsons - Assistant Company Secretary

020 7960 2228


16. Name and signature of authorised company official responsible for
making this notification


Gemma Parsons - Assistant Company Secretary


Date of notification


17.12.2008


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