SOURCE: Smith & Nephew PLC

April 10, 2007 09:42 ET

Smith & Nephew PLC announces Holding(s) in Company

London, UK -- (MARKET WIRE) -- April 10, 2007 --


       NOTIFICATION OF MAJOR INTERESTS IN SHARES



1. Name of company



Smith & Nephew plc



2. Name of shareholder having a major interest



Capital Research and Management Company



3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18



Non-beneficial



4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them



...............................................................


5. Number of shares / amount of stock acquired



...............................................................



6. Percentage of issued class



...............................................................





7. Number of shares / amount of stock disposed



15 million



8. Percentage of issued class



1.6%



9. Class of security



Ordinary shares of US 20 cents



10. Date of transaction



04.04.07



11. Date company informed



10.04.07



12. Total holding following this notification



121,149,464



13. Total percentage holding of issued class following this notification



12.9%



14. Any additional information



The Capital Group Companies Inc no longer reports ownership of securities,
Capital Research and Management Company and Capital Group International Inc, now
report relevant holdings separately for the purposes of the DTR Handbook.



15. Name of contact and telephone number for queries



Phil Higgins - Assistant Company Secretary

020 7960 2228



16. Name and signature of authorised company official responsible for making
this notification



Phil Higgins - Assistant Company Secretary



Date of notification



10.04.07



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END