SOURCE: Smith & Nephew PLC

October 21, 2008 12:11 ET

Smith & Nephew Plc - Holding(s) in Company

London, UK--(Marketwire - October 21, 2008) -


NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Name of company


Smith & Nephew plc 


2. Name of shareholder having a major interest


Capital Research and Management Company


3. Please state whether notification indicates that it is in respect of
holding of the shareholder named in 2 above or in respect of a
non-beneficial interest or in the case of an individual holder if it is
a holding of that person's spouse or children under the age of 18


Non-beneficial


4. Name of the registered holder(s) and, if more than one holder, the
number of shares held by each of them


Various

.............................



5. Number of shares / amount of stock acquired


475,975


6. Percentage of issued class


Less than 0.1%


7. Number of shares / amount of stock disposed



8. Percentage of issued class




9. Class of security


Ordinary shares of US 20 cents


10. Date of transaction


17.10.2008


11. Date company informed


20.10.2008


12. Total holding following this notification


44,594,320


13. Total percentage holding of issued class following this
notification


5.0527%


14. Any additional information



15. Name of contact and telephone number for queries


Gemma Parsons - Assistant Company Secretary

020 7960 2228


16. Name and signature of authorised company official responsible for
making this notification


Gemma Parsons - Assistant Company Secretary


Date of notification


21.10.2008


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