SOURCE: BioMedReports


January 14, 2011 07:01 ET

Special Report: Creating a Safer Treatment to Counteract the Effect of Blood Thinners

One Small Cap Biotech Company Seeks to Find Marketable Anticoagulant Reversal Agent That Will Save Lives

LOS ANGELES, CA--(Marketwire - January 14, 2011) - The search for viable alternatives to protamine is clearly an important one, but to date it has generated few successes. One prominent new player in the quest is PolyMedix, Inc. (OTCBB: PYMX), based in Radnor, Pennsylvania. The company has developed novel small molecules, which it has dubbed "heptagonists," that act to reverse the anticoagulant properties of both heparin and its low molecular weight variant. They are designed to be administered whenever bleeding that results from the use of blood thinners is diagnosed. 

The company has shown that its heptagonist compounds, including the lead compound known as PMX-60056, exhibits a number of positive characteristics that may make it useful for this purpose. 

PolyMedix has completed four clinical studies with PMX-60056, including three studies that were designed to assess efficacy. Their efforts would not represent the first attempt of their kind. The most significant previous attempt to create a marketable anticoagulant reversal agent took place about two decades ago, when Biomarin developed a drug known as heparinase. 

A free, full report special report titled: "A Red-Blooded Medical Challenge: Creating a Safer Treatment to Counteract the Effect of Blood Thinners" appears at

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