SOURCE: INGfertility


November 10, 2010 08:00 ET

Study at Recent ASRM Meeting Shows Unique Safety of Pre~Seed for Trying-to-Conceive Couples

SPOKANE, WA--(Marketwire - November 10, 2010) - The safety of Pre~Seed® (INGfertility®, Spokane, WA) as a fertility lubricant for trying-to-conceive couples was highlighted in a new study presented at the 2010 Annual Meeting of the American Society for Reproductive Medicine (ASRM) in Denver, CO. The study, conducted by Dr. RW Wright at Washington State University, evaluated the ability of sperm to fertilize and support normal embryo growth after contact with several personal lubricants.

This study showed that several lubricants containing glycerol (glycerin), even those that were labeled as a "fertility lubricant," caused sperm damage which led to embryo losses in an animal model. This may be due to toxic effects of ingredients, such as glycerol, on sperm prior to fertilizing an egg. In this study, food grade canola oil also caused sperm damage and resulted in abnormal embryo development. In contrast, sperm contact with Pre~Seed resulted in normal fertilization and embryo development, supporting its safe use in fertility patients.

The design of this study included sperm being exposed to the lubricants 30 minutes prior to fertilizing an egg in the laboratory and then allowing the embryos to grow over 7 days. The market leading lubricant, K-Y Jelly®, caused abnormal embryo development over 50% of the time. Other products marketed specifically to trying-to-conceive couples showed 30% or more abnormal embryo growth. The animal model was uniquely able to detect sublethal sperm damage from lubricant exposure which resulted in fertilization failure and embryo losses. Less complex studies commonly used to screen lubricants are unable to detect such damage.

GD Clifton (PharmD), CEO of INGfertility, stated, "Pre~Seed is the only product allowed to claim that it is safe to use when trying to conceive." Further he added, "These types of lubricant studies underscore the need for couples to be aware of lubricant choice when trying to conceive and that consumer safety should be increased by requiring lubricants to undergo testing for their impact on sperm and embryo development."

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