SOURCE: Essence of Life JIVA

June 12, 2008 22:39 ET

The Goodness of Red Wine, Sans the Alcohol

Harvard-Trained Doctor Develops Evidence-Based Nutraceutical, JIVA™ Resveratrol, to Deliver Heart-Protective Benefits of Red Wine in a Pill

GREENWICH, CT--(Marketwire - June 12, 2008) - It's called the French Paradox. The French eat a diet higher in fat than Americans, yet they suffer from less heart disease. Many scientists now believe the answer to this paradox lies in the copious amounts of red wine the French drink, since red wine contains a substance that's been shown to counteract the negative effects of a high-fat diet. The latest research confirms resveratrol may indeed have special heart-protective benefits, at lower doses than previously thought. There's just one problem: To get the amount of "low-dose" resveratrol studied, a person would have to drink 35 bottles of wine a day. Fortunately, Essence of Life offers high-potency resveratrol in pill form as JIVA Resveratrol (www.jivasupplements.org) -- delivering the goodness of red wine, without all the alcohol.

Few natural substances have generated as much excitement as resveratrol. It's been shown to increase the life spans of yeast, worms, fruit flies, and fish. In late 2006, researchers at Harvard Medical School and the National Institute on Aging created a stir when they published a study showing that mice fed a high-fat diet supplemented with resveratrol stayed just as healthy and active as mice eating a low-fat diet.(1) The latest research, published June 3 in the online journal Public Library of Science One, found that resveratrol inhibited a full 92 percent of age-related gene changes in the heart.(2)

The researchers noted they achieved this remarkable effect in mice with a much lower dose of resveratrol than used in previous studies: 4.9 milligrams/kilogram of body weight, which translates to 350 mg for a 160-pound person. But in red wine terms, that still equates to about 35 bottles per day. JIVA Resveratrol, on the other hand, provides 300 mg of the natural substance in just two easy-to-swallow capsules.

The product was formulated by Dr. Vijaya Nair, a Harvard-trained doctor and former professor of epidemiology at Columbia University School of Public Health. In developing her seven-product line of supplements, Dr. Nair searched for ingredients that fit two criteria. First, they had to address the most pressing health concerns of society today. Second, they had to be backed by a wealth of data substantiating their efficacy. Resveratrol was a natural fit on both counts.

However, in formulating JIVA Resveratrol, Dr. Nair went a step further, combining it with other heart-healthy ingredients, such as quercetin, guggul, and garlic. "It's not just resveratrol by itself," explains Dr. Nair. "It's a combination for cardiovascular health. So you're looking at stopping age-related genetic changes in the heart with resveratrol. You're looking at inhibiting inflammation of the cardiovascular system with quercetin. You're looking at preserving healthy cholesterol levels with guggul. And you're looking at maintaining healthy blood vessels with garlic."

The idea to combine resveratrol with quercetin is also backed by science. Studies in human tissues indicate that resveratrol may work better when quercetin is around. Why? Because inside the human body, resveratrol can become chemically bound to other substances, limiting its ability to be absorbed. But when quercetin is thrown into the mix, it keeps resveratrol unbound, which could improve its bioavailability.(3)(4)(5)

Always the scientist, Dr. Nair cautions that JIVA Resveratrol will not cure someone with cardiac failure. It's meant for people who want to keep their hearts as healthy as possible, even as they age. With a recent survey showing heart health tops the list of Americans' most pressing health concerns, it looks like she'll have a lot of customers.(6)

About Essence of Life

Essence of Life was co-founded by Dr. Vijaya Nair, a recognized expert in the field of alternative treatments for cancer and HIV/AIDS, and Omer L. Rains, a three-term California senator who met Dr. Nair at Columbia University when his brother fell ill with cancer. The JIVA product line includes seven evidence-based nutraceuticals that integrate the timeless practices of Ayurvedic and Traditional Chinese Medicine into signature, plant-based formulas. The name of the product line -- which means "essence of life" in Sanskrit -- embodies the company's mission: to provide its customers with the essence of health and well-being.

JIVA products are available online at www.jivasupplements.org. and in leading natural health stores.

(1) Baur JA, et al. Resveratrol improves health and survival of mice on a high-calorie diet. Nature. 2006 Nov 16;444(7117):337-42.

(2) Barger JL. A low dose of dietary resveratrol partially mimics calorie restriction and retards aging parameters in mice. PLoS ONE. 2008. 3(6): e2264. doi:10.1371/journal.pone.0002264.

(3) de Santi C, et al. Glucuronidation of resveratrol, a natural product present in grape and wine, in the human liver. Xenobiotica. 2000 Nov;30(11):1047-54.

(4) de Santi C, et al. Sulphation of resveratrol, a natural compound present in wine, and its inhibition by natural flavonoids. Xenobiotica. 2000 Sep;30(9):857-66.

(5) de Santi C, et al. Sulphation of resveratrol, a natural compound present in wine, in the human liver and duodenum. Xenobiotica. 2000 Jun;30(6):609-17.

(6) What are Americans' Most Pressing Health Concerns? Robert Wood Johnson Foundation. Number 18, Feb. 2007. http://www.rwjf.org/files/publications/other/Research%20Highlight%2018%5B5%5D.pdf

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