SOURCE: SRI International

SRI International

August 04, 2009 11:30 ET

Twin Research Registry at SRI International Seeks Twin Pairs for Seasonal Flu Vaccine Study at Stanford University

MENLO PARK, CA--(Marketwire - August 4, 2009) - SRI International, an independent, nonprofit research and development institute, is seeking healthy fraternal and identical twin pairs of a variety of ages to participate in a National Institutes of Health-sponsored study to develop more effective flu vaccines.

All volunteer participants will receive the licensed, approved seasonal influenza vaccine that will also be given to the public this flu season. Volunteers of the following ages are currently needed:

--  8-17  (with parent or guardian registration and approval)
--  18-30
--  40-49
--  70-100

The Stanford University School of Medicine-led research study, conducted by Mark Davis, Ph.D., professor of microbiology and immunology, and Cornelia L. Dekker, M.D., professor of pediatrics, will examine the immune system's response to immunization against influenza -- commonly known as "the flu."

Researchers will also investigate markers and mechanisms that can be predictors for immunological health. The study presents researchers with an opportunity to determine how individual responses to the vaccine vary as a function of age and genetic factors.

Fraternal and identical twin pairs are a valuable resource to science, and have helped researchers identify genetic and environmental sources of variation in a number of health-related conditions. Gary Swan, Ph.D., director of SRI's Center for Health Sciences, which includes the Twin Research Registry™ at SRI International, is partnering with the Stanford team to interpret the results of the twin pairs who receive the seasonal flu vaccine.

"Twin research studies have provided important genetic clues to a variety of health issues, from heart disease to diabetes and nicotine addiction," said Dr. Swan. "We are pleased to work together with Stanford researchers on this important study and to speak with twins about this opportunity to get a free flu vaccine and help scientists develop a better understanding of how the body responds to the vaccine at the same time."

Volunteers can join the Twin Research Registry at SRI International (, a valuable science resource that reflects the diverse population of the region. The registry was established in 1995 by SRI's Center for Health Sciences, and currently includes more than 2,600 twin registrants. Registry members have participated in studies focusing on the pharmacokinetics of nicotine, metabolism of commonly used medications, genetic susceptibility to cancer-causing chemicals, and sleep patterns in young twins.

To volunteer or for more information, call 1-800-SRI-TWIN (1-800-774-8946) or visit

About SRI's Center for Health Sciences

Serving government and commercial clients in the health arena, SRI's Center for Health Sciences uses a multidisciplinary research approach to address complex challenges that arise at the interface of the basic sciences, clinical medicine, health care economics, and the regulatory and legal environments.

About SRI International

Silicon Valley-based SRI International ( is one of the world's leading independent research and technology development organizations. SRI, which was founded by Stanford University as Stanford Research Institute in 1946 and became independent in 1970, has been meeting the strategic needs of clients and partners for more than 60 years. Perhaps best known for its invention of the computer mouse and interactive computing, SRI has also been responsible for major advances in networking and communications, robotics, drug discovery and development, advanced materials, atmospheric research, education research, economic development, national security, and more. The nonprofit institute performs sponsored research and development for government agencies, businesses, and foundations. SRI also licenses its technologies, forms strategic alliances, and creates spin-off companies. In 2008, SRI's consolidated revenues, including its wholly owned for-profit subsidiary, Sarnoff Corporation, were approximately $490 million.

About Stanford University Medical Center

Stanford University Medical Center integrates research, medical education and patient care at its three institutions -- Stanford University School of Medicine, Stanford Hospital & Clinics and Lucile Packard Children's Hospital at Stanford. For more information, please visit the Web site of the medical center's Office of Communication & Public Affairs at and the Stanford-LPCH Vaccine Program Web site at

Contact Information

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    Dina Basin
    SRI International
    (650) 859-3845
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