November 14, 2006 13:00 ET Reports That the Use of Personal Permanent Hair Dye Is Not Linked to Bladder Cancer Risk

BERKELEY, CA -- (MARKET WIRE) -- November 14, 2006 -- UroToday reports on a study determining if there is a link between the use of Permanent Hair Dye and the development of bladder cancer. Christopher P. Evans, M.D. reports on the following:

An occupational exposure to hair dyes by hairdressers and barbers is shown to increase their bladder cancer risk. Hair dyes contain small amounts of aromatic amines, which are shown to be carcinogenic in animals. Prior to 1980, the formulations contained much higher contents of carcinogens. In the September 2006 issue of Cancer Epidemiology Biomarkers and Prevention, researchers from M.D. Anderson Cancer Center report that personal use of hair dyes does not increase the risk of bladder cancer.

The study included 712 bladder cancer cases and 712 healthy controls from M.D. Anderson Cancer Center and Baylor College of Medicine. All cases were newly diagnosed and had not received chemotherapy or radiotherapy. Demographic data was collected to include tobacco use, work history and personal hair dye use.

The bladder cancer cohort had a higher percentage of current (27%) and ever smokers (73%) compared to controls (9% and 52%). The percentage of cases reporting ever use of hair dye was similar to that of the controls. The odds ratio for any use of hair dye products did not demonstrate a difference. The association between duration of use, frequency of use, lifetime use, age at first use and bladder cancer risk showed no associations. Even patients using the more carcinogenic versions of hair dyes prior to 1980 were not found to be at increased risk.

These data suggest that permanent hair dye usage does not contribute to the development of bladder cancer.


Cancer Epidemiol Biomarkers Prev 2006;15:1746-1749 September 2006

Jie Lin, Colin P. Dinney, H. Barton Grossman, and Xifeng Wu: E-mail:

By Christopher P. Evans, M.D. -- the only urology website with original content written by global urology key opinion leaders actively engaged in clinical practice.

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