TORONTO, ON--(Marketwired - November 04, 2016) - In an informative session, industry expert Nicola Tonge, Histology Manager & Immunohistochemistry Specialist at Epistem will aim to inform scientists considering the use of immunohistochemistry (IHC) as a readout for target and biomarker validation. The webinar will illustrate the depth of knowledge that can be generated by IHC, and indicate its limitations. An overview of IHC methods will be provided, from tissue fixation, antigen retrieval, to amplification and detection methods. The presenter will discuss the factors to consider in protocol development, validation, automation and quantification, particularly for clinical biomarkers, along with some key examples of biomarker expression in both target tissues, such as tumours and surrogate biomarker tissues, including the use of IHC on individual plucked human hairs. Historical data will be presented to illustrate the techniques and solutions to common problems.
The speaker will outline the common problems that she has experienced working with many different biotechnology and pharmaceutical companies in this area over the last 14 years.
Specifically, there will be an overview of: protocol development, protocol validation, and image analysis techniques.
Join Nicola Tonge on Monday, November 21, 2016 at 10am EST (3pm GMT/UK). For more information or to register for this complimentary event, visit: The Use of Immunohistochemistry in Target and Biomarker Validation
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