SOURCE: Wall Street News Alert

Wall Street News Alert

February 27, 2008 08:48 ET

Wall Street News Alert: ELHI Is Wednesday's Stock to Watch for February 27, 2008

NOTE TO EDITORS: The Following Is an Investment Opinion Being Issued by Wall Street Capital Funding.

WESTON, FL--(Marketwire - February 27, 2008) - Wall Street News Alert's "stocks to watch" this morning are: Edgeline Holdings, Inc. (OTCBB: ELHI), Prana Biotechnology Limited (NASDAQ: PRAN), Citi (NYSE: C) and Intel Corporation (NASDAQ: INTC).

Having previously announced an agreement that provides enabling technology for its lead clinical program, Edgeline Holdings, Inc. (OTCBB: ELHI), which recently announced a name change to Oncolin Therapeutics Inc., continues to be a "must see" for investors. Yesterday after the markets closed, the company issued a press release announcing that it has agreed to terms for an exclusive worldwide right to option patents covering the composition and use of Genistein analogs for cancer treatment.

This is more great news for the company! The technology was discovered and patented by the Pharmaceutical Research Institute of Warsaw, Poland and involves compounds that appear to be novel antimicrotubule agents. The press release states that given the widespread success of antimicrotubule therapies in curative and palliative cancer treatment, the microtubule is perhaps the single best cancer target identified to date and continues to be recognized as a strategic target against which to direct new development efforts.

The approved drugs from this mechanistic class include the Vinca alkaloids such as vincristine, the taxanes with paclitaxel and docetaxel and the epothilones with its first drug recently approved by Bristol Myers. Each of these different types of compound classes appear to interact at different parts of the microtubule and have different spectrums of activity and show effectiveness against resistant disease.

"We are very excited to have the opportunity to develop what may be yet another unique antimicrotubule class of compounds. This specific mechanism continues to be of great interest to the cancer research community as it may provide yet another different spectrum of activity in the clinic," said Dr Donald Picker, COO of the company.

This is Big, Big business! According to an article in BusinessWeek, the cancer-therapies market is estimated to be approximately $32 billion and is forecast to grow to between $55 billion and $70 billion by 2010, according to a report by market research firm Frost & Sullivan. The disease's high incidence rate and the lack of drugs and therapies that can either cure it or increase the life-expectancy period of patients is driving the discovery of novel agents.

There have been major announcements coming from the company! This month the company reported that one of its research programs for which it has rights was awarded a peer reviewed National Institute Of Health Grant for $179,000 to support research on thermally targeted delivery of Doxorubicin.

In other recent news: Edgeline Holdings, Inc. has recently announced it has obtained an exclusive option agreement with The University of Texas M.D. Anderson Cancer Center which provides the Company the right to negotiate a license for five technologies relating to the treatment of various cancers over a nine month period.

Edgeline Holdings, Inc. has recently announced a Joint Development Agreement with Houston Pharmaceuticals to assist the Company in obtaining a license for certain patents.

Prior to the latest press release, the stock closed Tuesday at Forty cents a share.

For an in-depth profile of Edgeline Holdings, visit http://www.WallStreetNewsAlert.com/HotStocks/ELHI022608/default.aspx.

Prana Biotechnology Limited (NASDAQ: PRAN) up 36.3% on 1.7 million shares traded.

Prana Biotechnology was established to commercialise research into Alzheimer's disease and other major age-related neurodegenerative disorders.

Citi (NYSE: C) up 0.8% on 104 million shares traded.

Citi, the leading global financial services company, has some 200 million customer accounts and does business in more than 100 countries, providing consumers, corporations, governments and institutions with a broad range of financial products and services, including consumer banking and credit, corporate and investment banking, securities brokerage, and wealth management.

Intel Corporation (NASDAQ: INTC) up 3.7% on 78.3 million shares traded.

Intel, the world leader in silicon innovation, develops technologies, products and initiatives to continually advance how people work and live.

Market Commentary:

"Battered by bad economic news, consumer confidence plunged while wholesale food, energy and medicine costs soared, pushing inflation up at the fastest pace in a quarter century," stated Sonja Rudd in Wall Street News Alert's daily commentary continued at: http://www.WallStreetNewsAlert.com.

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