SOURCE: Wall Street News Alert

Wall Street News Alert

February 27, 2008 09:38 ET

Wall Street News Alert: Investment Watch: ELHI! February 27, 2008

NOTE TO EDITORS: The Following Is an Investment Opinion Being Issued by Wall Street Capital Funding.

WESTON, FL--(Marketwire - February 27, 2008) - Wall Street News Alert's "stocks to watch" this morning are: Edgeline Holdings, Inc. (OTCBB: ELHI), CollaGenex Pharmaceuticals Incorporated (NASDAQ: CGPI), Microsoft Corporation (NASDAQ: MSFT) and EMC Corporation (NYSE: EMC).

Having previously announced an agreement that provides enabling technology for its lead clinical program, Edgeline Holdings, Inc. (OTCBB: ELHI), which recently announced a name change to Oncolin Therapeutics Inc., continues to be a "must see" for investors. Yesterday after the markets closed, the company issued a press release announcing that it has agreed to terms for an exclusive worldwide right to option patents covering the composition and use of Genistein analogs for cancer treatment.

This is more great news for the company! The technology was discovered and patented by the Pharmaceutical Research Institute of Warsaw, Poland and involves compounds that appear to be novel antimicrotubule agents. The press release states that given the widespread success of antimicrotubule therapies in curative and palliative cancer treatment, the microtubule is perhaps the single best cancer target identified to date and continues to be recognized as a strategic target against which to direct new development efforts.

The approved drugs from this mechanistic class include the Vinca alkaloids such as vincristine, the taxanes with paclitaxel and docetaxel and the epothilones with its first drug recently approved by Bristol Myers. Each of these different types of compound classes appear to interact at different parts of the microtubule and have different spectrums of activity and show effectiveness against resistant disease.

"We are very excited to have the opportunity to develop what may be yet another unique antimicrotubule class of compounds. This specific mechanism continues to be of great interest to the cancer research community as it may provide yet another different spectrum of activity in the clinic," said Dr Donald Picker, COO of the company.

This is Big, Big business! According to an article in BusinessWeek, the cancer-therapies market is estimated to be approximately $32 billion and is forecast to grow to between $55 billion and $70 billion by 2010, according to a report by market research firm Frost & Sullivan. The disease's high incidence rate and the lack of drugs and therapies that can either cure it or increase the life-expectancy period of patients is driving the discovery of novel agents.

There have been major announcements coming from the company! This month the company reported that one of its research programs for which it has rights was awarded a peer reviewed National Institute Of Health Grant for $179,000 to support research on thermally targeted delivery of Doxorubicin.

In other recent news: Edgeline Holdings, Inc. has recently announced it has obtained an exclusive option agreement with The University of Texas M.D. Anderson Cancer Center which provides the Company the right to negotiate a license for five technologies relating to the treatment of various cancers over a nine month period.

Edgeline Holdings, Inc. has recently announced a Joint Development Agreement with Houston Pharmaceuticals to assist the Company in obtaining a license for certain patents.

Prior to the latest press release, the stock closed Tuesday at Forty cents a share.

For an in-depth profile of Edgeline Holdings, visit

CollaGenex Pharmaceuticals Inc (NASDAQ: CGPI) up 27.5% on 18.1 million shares traded.

CollaGenex Pharmaceuticals, Inc. is a specialty pharmaceutical company currently focused on developing and marketing proprietary, innovative medical therapies to the dermatology market.

Microsoft Corp. (NASDAQ: MSFT) up 1.9% on 99.7 million shares traded.

Founded in 1975, Microsoft is the worldwide leader in software, services and solutions that help people and businesses realize their full potential.

EMC Corporation (NYSE: EMC) up 2.6% on 37.7 million shares traded.

EMC Corporation is the world's leading developer and provider of information infrastructure technology and solutions that enable organizations of all sizes to transform the way they compete and create value from their information.

Market Commentary:

"Oil futures surged to close at a new record Tuesday! Light, sweet crude for April delivery jumped $1.65 to settle at $100.88 a barrel on the New York Mercantile Exchange. At one point in the session, prices surged as high as $101.15," stated Sonja Rudd in Wall Street News Alert's daily commentary continued at:

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